Synthesis of new 2,5-disubstituted-1,3,4-thiadiazole derivatives and their in vivo anticonvulsant activity [PDF]
A series of 2,5-disubstituted-1,3,4-thiadiazole derivatives were synthesized by the reaction of 3-(2-cyanopropan-2-yl)-N-(5-(piperazine-1-yl)-1, 3,4-thiadiazol-2-yl)benzamide with various sulfonyl chlorides and evaluated for their anticonvulsant activity
Harish, K. P. +2 more
core +3 more sources
Challenges in the future of cancer screening
Abstract The purpose of cancer screening is to reduce mortality, and ideally incidence, from the cancer screened for. Until recently, cancer screening has been offered to all persons in pre‐defined sex‐ and age‐groups. The exception is lung screening which is targeted to high‐risk individuals.
Elsebeth Lynge +29 more
wiley +1 more source
Biomolecular mechanisms of staphylococcal biofilm formation [PDF]
The multitude of biomolecular and regulatory factors involved in staphylococcal adhesion and biofilm formation owe much to their ability to colonize surfaces, allowing the biofilm form to become the preferential bacterial phenotype.
Gilmore, Brendan F +3 more
core +1 more source
Evaluation of biofilm production and prevalence of theicaDgene in methicillin-resistant and methicillin-susceptibleStaphylococcus aureusstrains isolated from patients with nosocomial infections and carriers [PDF]
Staphylococcus aureus is one of the most important etiological agents responsible for healthcare-associated infections and is capable of producing many virulence factors including biofilm. The aim of the present study was to analyze the correlation between the presence of the icaD and icaA genes and the ability to produce biofilm in vitro in 302 ...
Mariusz, Grinholc +2 more
openaire +2 more sources
In symptomatic, atherosclerotic middle cerebral artery stenosis: Relative WSS (rWSS) increased progressively along upstream plaque segment but highly varied downstream. Relative WSS (rWSS) was lower on the inner than outer wall of the MCA‐M1 vessel curve. Ventrally and inferiorly oriented middle cerebral artery trunk and higher tortuosity of the vessel
Linfang Lan +22 more
wiley +1 more source
Staphylococci are a common cause of catheter-associated urinary tract infections. The present study evaluated biofilm forming capacity and the presence of both icaA and icaD genes among staphylococci strains isolated from patients undergoing ureteral catheterization.Different bacterial strains were isolated from urine and stents segments collected from
Gamal Fadl Mahmoud Gad +5 more
openaire +4 more sources
A Case of Bilateral Globus Pallidus Infarction Onset With Mental Disorder
Bilateral globus pallidus lesions are closely linked to neuropsychiatric manifestations; however, bilateral globus pallidus infarction is frequently misdiagnosed owing to its nonspecific clinical presentation. We report a 45‐year‐old female patient who initially presented with mental disturbance (akinetic mutism, memory impairment, and sleep rhythm ...
Yingxia Li +3 more
wiley +1 more source
Intracranial stenosis and longitudinal progression of Alzheimer's disease pathologies
Abstract INTRODUCTION The relationship between intracranial stenosis (ICS) and Alzheimer's disease (AD) pathologies remains unclear. We investigated whether baseline ICS is associated with longitudinal changes in amyloid beta (Aβ) and tau deposition. METHODS We prospectively followed 180 older adults (mean age 70.06 ± 7.40 years), including cognitively
Koung Mi Kang +13 more
wiley +1 more source
High cell density and latent membrane protein 1 expression induce cleavage of the mixed lineage leukemia gene at 11q23 in nasopharyngeal carcinoma cell line [PDF]
Background Nasopharyngeal carcinoma (NPC) is commonly found in Southern China and South East Asia. Epstein-Barr virus (EBV) infection is well associated with NPC and has been implicated in its pathogenesis.
Peter Yee, Sai-Peng Sim
core +3 more sources
Staphylococcus spp. es una causa importante de infecciones asociadas con el cateterismo urinario y otros dispositivos médicos. La formación de biopelículas es un paso importante en la patogénesis de estos estafilococos y depende de la expresión del operón icaADBC involucrado en la síntesis de una adhesión intercelular de polisacáridos. En este estudio,
Kara Terki Ibtissem +6 more
openaire +2 more sources

