Results 111 to 120 of about 10,367,086 (312)

Comparison of Diagnosis Codes to Clinical Notes in Classifying Patients with Diabetic Retinopathy

Ophthalmology Science
Purpose: Electronic health records (EHRs) contain a vast amount of clinical data. Improved automated classification approaches have the potential to accurately and efficiently identify patient cohorts for research.
Sean Yonamine, MPH, Chu Jian Ma, MD, PhD, Rolake O. Alabi, MD, PhD, Georgia Kaidonis, MBBS, PhD, Lawrence Chan, MD, Durga Borkar, MD, Joshua D. Stein, MD, MS, Benjamin F. Arnold, PhD, Catherine Q. Sun, MD   +8 more
doaj   +1 more source

ICD-10 coding algorithms for defining comorbidities of acute myocardial infarction

BMC Health Services Research, 2006
Background With the introduction of ICD-10 throughout Canada, it is important to ensure that Acute Myocardial Infarction (AMI) comorbidities employed in risk adjustment methods remain valid and robust.
Evans Dewey, So Lawrence, Quan Hude
doaj   +1 more source

ICD-10 codes used to identify relevant diagnosis groups.

ICD-10 codes used to identify relevant diagnosis groups.
Christopher Inchley (13521115), Astrid Elisabeth Rojahn (13521100), Anne-Marte Bakken Kran (11904228), Ketil Størdal (4232854), Elisebet Haarr (13521109), Truls Michael Leegaard (12062588), Håkon Bøås (789642), Lise Beier Havdal (13521097), Henrik Døllner (3150504), Elmira Flem (3186711), Svein Arne Nordbø (3150510), Terese Bekkevold (11505913), Bjørn Barstad (13521106), Sara Debes (13521103)   +13 more
core   +1 more source

Spatiotemporally Ultrasound‐Controlled Nanoparticles Reprogramming Immunostimulatory Antigen‐Presenting Cancer‐Associated Fibroblasts to Enhance Cancer Immunotherapy

Advanced Science, EarlyView.
We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai, Weikai Sun, Yuxuan Zhao, Daqian Sun, Ting Meng, Yafei Qi, Fengyang Jiang, Jintang Sun, Zhiliang Gao, Dexin Yu   +9 more
wiley   +1 more source

Coding rules for uncertain and “ruled out” diagnoses in ICD-10 and ICD-11

BMC Medical Informatics and Decision Making
The International Classification of Diseases, 11th Revision (ICD-11) has significantly improved the ability to navigate coding challenges beyond prior iterations of the ICD.
Oluseun O. Atolagbe, Patrick S. Romano, Danielle A. Southern, Wachira Wongtanasarasin, William A. Ghali   +4 more
doaj   +1 more source

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

Advanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan, Zifan Pei, Jie Wu, Nan Jiang, Qian Li, Yuqi Yang, Jie Cao, Yechen Huang, Shumin Sun, Qialu Du, Zhicheng Liu, Lin Zhang, Fei Gong, Jinhua Zhou, Liang Cheng   +14 more
wiley   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Evaluation of Emergency Department Admissions in Syrian Patients Aged Under Eighteen Years of Age Between 2012 and 2016 in the City of Hatay

Journal of Pediatric Emergency and Intensive Care Medicine, 2019
Introduction:Wars are disasters leading to irreversible consequences that affect great numbers of people. Injuries and deaths are considered to be direct effects of wars and these effects are felt more in places near war zones.
Ezgi Atalay, Ali Karakuş, Galip Usta
doaj   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

Advanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang, Yuhang Tang, Ronghao Yue, Jingtao Xu, Yong Tao, Jie Chen, Shipeng Li, Guosheng Zhao, Jinfang Xue, Mingwei Sun, Fenglei Gao, Yunsheng Ou, Yang Wang   +12 more
wiley   +1 more source

ICD-10 codes used to classify external cause injuries.

ICD-10 codes used to classify external cause injuries.
Sarah Paleczny (18078096), Nosakhare Osagie (18078099), Jai Sethi (18078102)   +2 more
core   +1 more source