Results 141 to 150 of about 10,190,762 (331)

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Help, my rating looks bad! Coding comorbidities in arthroplasty

Arthroplasty Today, 2016
In medicine today, there is a trend toward increasing transparency. Higher quality and better value are being sought, and one of the methods being used is publicly reported health care outcomes.
Joseph D. Galloway, MD, Frank R. Voss, MD   +1 more
doaj   +1 more source

Prevalence and use of services in persons with schizophrenia and related disorders in Málaga (Spain) [PDF]

, 2013
Background/Objectives Very few studies have examined schizophrenia morbidity in Spain, using multiple sources of information. We performed a 1-year prevalence study of schizophrenia and related disorders in Málaga and the use of services in a population
Angona, Pedro, García-Herrera, José María, Martín, Carlos, Mayoral Cleries, Fermín, Moreno-Kustner, Berta, Navas Campaña, Desirée María, Rivas, Fabio   +6 more
core  

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Comparison of Diagnosis Codes to Clinical Notes in Classifying Patients with Diabetic Retinopathy

Ophthalmology Science
Purpose: Electronic health records (EHRs) contain a vast amount of clinical data. Improved automated classification approaches have the potential to accurately and efficiently identify patient cohorts for research.
Sean Yonamine, MPH, Chu Jian Ma, MD, PhD, Rolake O. Alabi, MD, PhD, Georgia Kaidonis, MBBS, PhD, Lawrence Chan, MD, Durga Borkar, MD, Joshua D. Stein, MD, MS, Benjamin F. Arnold, PhD, Catherine Q. Sun, MD   +8 more
doaj   +1 more source

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Are ICD-10 categories suitable for diagnosing injuries? Multidisciplinary analyses of the English, German, and Hungarian ICD-10 diagnosis categories

Scripta Manent, 2019
ICD-10 is a standardized diagnostic tool of the World Health Organization (WHO) for the documentation of findings to facilitate statistical comparability. It enhances fast diagnosis documentation using a globally readable coding.
Katalin Fogarasi, Alexandra Csongor, Philipp Schneider   +2 more
doaj  

Evaluation of Emergency Department Admissions in Syrian Patients Aged Under Eighteen Years of Age Between 2012 and 2016 in the City of Hatay

Journal of Pediatric Emergency and Intensive Care Medicine, 2019
Introduction:Wars are disasters leading to irreversible consequences that affect great numbers of people. Injuries and deaths are considered to be direct effects of wars and these effects are felt more in places near war zones.
Ezgi Atalay, Ali Karakuş, Galip Usta
doaj   +1 more source