Results 61 to 70 of about 271,547 (325)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Problematic gaming exists and is an example of disordered gaming [PDF]

, 2017
Background: The recent paper by Aarseth et al. (2016) questioned whether problematic gaming should be considered a new disorder particularly because “Gaming Disorder” (GD) has been identified as a disorder to be included in the next (11th) revision of ...
Aarseth, Aarseth, Andreassen, Andreassen, Fuster, Fuster, Gentile, Gentile, Griffiths, Griffiths, Griffiths, Griffiths, Griffiths, Griffiths, Hebebrand, Hebebrand, Keepers, Keepers, Khazaal, Khazaal, King, King, King, King, Király, Király, Király, Király, Kraus, Kraus, Kuczmierczyk, Kuczmierczyk, Kuss, Kuss, Kuss, Kuss, Kuss, Kuss, Kuss, Kuss, Lee, Lee, Lemmens, Lemmens, Lemmens, Lemmens, Maraz, Maraz, Maraz, Maraz, Monacis, Monacis, Mónok, Mónok, Müller, Müller, Nilles, Nilles, Omurtag, Omurtag, Park, Park, Petry, Petry, Pontes, Pontes, Pontes, Pontes, Pontes, Pontes, Pontes, Pontes, Pontes, Pontes, Pontes, Pontes, Pontes, Pontes, Rehbein, Rehbein, Ross, Ross, Sakuma, Sakuma, Shaffer, Shaffer, Shotton, Shotton, Targhetta, Targhetta, Tejeiro, Tejeiro, Wenzel, Wenzel, Wittek, Wittek, Yao, Yao, Young, Young   +99 more
core   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Balancing between prejudice and fact for Gaming Disorder: Does the existence of alcohol use disorder stigmatize healthy drinkers or impede scientific research? [PDF]

, 2017
The inclusion of Gaming Disorder (GD) criteria in the 11th Revision of the International Classification of Diseases (ICD-11) beta draft was recently criticized, and an argument was made for its removal to “avoid a waste of public resources.” However ...
Choo, Hyekyung, Lee, Hae Kook, Lee, Seung-Yup   +2 more
core   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

ICD-11 for quality and safety: overview of the who quality and safety topic advisory group [PDF]

, 2017
This paper outlines the approach that the WHO's Family of International Classifications (WHO-FIC) network is undertaking to create ICD-11. We also outline the more focused work of the Quality and Safety Topic Advisory Group, whose activities include the ...
Brien, Susan E., Burnand, Bernard, Colin, Cyrille, Drösler, Saskia E., Forster, Alan J., Ghali, William A., Gurevich, Yana, Harrison, James, Kostanjsek, Nenad, Moskal, Lori, Munier, William B., Pincus, Harold A., Quan, Hude, Romano, Patrick S., Southern, Danielle A., Spaeth-Rublee, Brigitta, Sundararajan, Vijaya, Üstün, T. Bedirhan   +17 more
core  

Anxiety and Posttraumatic Stress Disorder in the Context of Human Brain Evolution:A Role for Theory in DSM-V? [PDF]

, 2008
The “hypervigilance, escape, struggle, tonic immobility”\ud evolutionarily hardwired acute peritraumatic response\ud sequence is important for clinicians to understand. Our\ud commentary supplements the useful article on human\ud tonic immobility (TI) by
Bracha, Dr. H. Stefan, Maser, Dr. Jack D.   +1 more
core   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Social (pragmatic) communication disorders and autism spectrum disorder [PDF]

, 2015
Changes have been made to the diagnostic criteria for autism spectrum disorder (ASD) in the recent revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), and similar changes are likely in the WHO International Classification of ...
Baird, G, Norbury, CF
core  

Re-experiencing traumatic events in PTSD: new avenues in research on intrusive memories and flashbacks [PDF]

, 2015
Posttraumatic flashbacks, consisting of the intrusive re-experiencing of traumatic experiences in the present, have been more clearly defined for the first time in DSM-5 and have been identified as a unique symptom of posttraumatic stress disorder in the
Brewin, CR
core   +2 more sources