Results 191 to 200 of about 547,458 (298)

High Prevalence of SOD1 Pathogenic Variants in the UK Biobank: Implications for Early Intervention in Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective SOD1 is the second most frequently mutated gene in European patients with amyotrophic lateral sclerosis (ALS). Given the recent authorization of SOD1‐targeted antisense oligonucleotides for SOD1‐ALS, prompt screening for SOD1 mutations in patients with ALS patients is highly recommended.
Delia Gagliardi, Chiara Villella, Matteo Zanovello, Virginia Iacobelli, Stefania Corti, Giacomo Pietro Comi, Pietro Fratta, Henry Houlden, Arianna Tucci, Dario Ronchi   +9 more
wiley   +1 more source

Positive Predictive Values of ICD-10-CM Diagnostic Codes in Identifying Diabetic Macular Edema in Claims Data: A Multi-Institutional Study in Taiwan. [PDF]

Clin Epidemiol
Huang YC, Hwang YS, Wu WC, Lai CC, Yeung L, Shao SC.   +5 more
europepmc   +1 more source

Pre‐Diagnostic Plasma Carotenoids, Tocopherols and Retinol Levels, and Risk of Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective Our goal was to examine whether pre‐diagnostic plasma carotenoids and tocopherols are associated with amyotrophic lateral sclerosis (ALS). Methods A nested case–control study within 4 United States cohorts, where 154 participants with pre‐diagnostic blood‐draw, were diagnosed during follow‐up with amyotrophic lateral sclerosis (ALS). Controls
Éilis J. O'Reilly, Kjetil Bjornevik, Jeremy D. Furtado, Alpa V. Patel, Ying Wang, Laurence N. Kolonel, Loïc Le Marchand, Alberto Ascherio   +7 more
wiley   +1 more source

Enhancing detection of severe enterovirus infections: A data linkage study of ICD-10 codes with national enterovirus laboratory data, Denmark, 2010 to 2023. [PDF]

Euro Surveill
Johannesen CK, Egeskov-Cavling AM, Lange T, Krause TG, Jepsen MPG, Nygaard U, Midgley SE, Franck KT, Fischer TK.   +8 more
europepmc   +1 more source

O‐Terphenyl‐basierte Familie konjugierter Makrozyklen: Selektive Erkennung von Phenylalanin im Wasser und Interaktion mit Insulin

Angewandte Chemie, EarlyView.
Diese Studie beschreibt die Herstellung und Eigenschaften einer neuen Familie von o‐Terphenyl‐basierten Makrozyklen, TP[n] (n = 2‐8). Der Trimer bindet Phenylalanin in Wasser sehr effizient und ist dabei zehnmal selektiver als bei anderen Aminosäuren und aromatischen Neurotransmittern.
Swapnil Ghule, Sayan Sarkar, Maria Eugenia Pérez‐Ojeda Rodriguez, Mark Spector, Frank Hampel, Evgeny A. Kataev   +5 more
wiley   +1 more source

Post-COVID-19 conditions identified by ICD-10-CM code in a cohort of U.S. primary care patients, 2021 - 2023. [PDF]

J Multimorb Comorb
Wang X, Velásquez E, Saydah S, Koumans EH, Rochlin I, Romano S, Rehkopf DH, Ford ND.   +7 more
europepmc   +1 more source

o‐Terphenyl‐Based Family of Conjugated Macrocycles: Selective Recognition of Phenylalanine in Water and Interaction With Insulin

Angewandte Chemie International Edition, EarlyView.
This study presents the synthesis and binding properties of a new family of o‐terphenyl‐based macrocycles, TP[n] (n = 2‐8). The trimer variant efficiently binds phenylalanine in water with a 10‐fold selectivity compared to other amino acids and aromatic neurotransmitters.
Swapnil Ghule, Sayan Sarkar, Maria Eugenia Pérez‐Ojeda Rodriguez, Mark Spector, Frank Hampel, Evgeny A. Kataev   +5 more
wiley   +1 more source

Data report about course on underlying cause-of-death coding (ICD-10): the case virtual learning environment of the Brazilian health system. [PDF]

Front Digit Health
Doreto AJ, Teixeira AM, Valentim JLRS, Santos JPQ, Pinto TKB, Mendes YMMB, Dias AP, Coutinho KMD, Gonçalves EN, Pinheiro AS, Fernandes F, Batista NAN, Coutinho KD, Valentim RAM.   +13 more
europepmc   +1 more source