Results 31 to 40 of about 289,189 (260)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Cause of death coding in asthma

BMC Medical Research Methodology
Background While clinical coding is intended to be an objective and standardized practice, it is important to recognize that it is not entirely the case.
Alexandria Chung, George Addo Opoku-Pare, Holly Tibble   +2 more
doaj   +1 more source

An account of psychiatric casework in three clinical encounters using a psychoanalytic lens

Annals of Indian Psychiatry, 2017
Transference and countertransference are key diagnostic concepts in psychoanalysis which are unacknowledged in categorical diagnostic systems in psychiatry. This may also highlight the fundamental differences in understanding clinical presentation in the
Anuradha Menon
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Association between symptoms of unipolar depression and metabolic syndrome in a tertiary care hospital

Telangana Journal of Psychiatry, 2019
Introduction: Depression is associated with increased physical co-morbid conditions. The results of previous studies on the relationship between symptoms of depression and metabolic syndrome are weak.
Md Munnawar S Hussain, Raj Kumar Lenin Singh, Amol Patange, Ningombam Heramani Singh, Thingbaijam Bihari Singh, Goejendro Singh   +5 more
doaj   +1 more source

Transforming the German ICD-10 (ICD-10-GM) into Injury Severity Score (ISS)-Introducing a new method for automated re-coding.

PLoS ONE, 2021
BackgroundWhile potentially timesaving, there is no program to automatically transform diagnosis codes of the ICD-10 German modification (ICD-10-GM) into the injury severity score (ISS).ObjectiveTo develop a mapping method from ICD-10-GM into ICD-10 ...
Marcel Niemann, Sven Märdian, Pascal Niemann, Liv Tetteh, Serafeim Tsitsilonis, Karl F Braun, Ulrich Stöckle, Frank Graef   +7 more
doaj   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

ICD-11 pilot in West China: feasibility evaluation and implications for future implementation

Scientific Reports
This study was designed to comprehensively evaluate the feasibility of implementing ICD-11 as a replacement for ICD-10 in West China in terms of morbidity and mortality coding, summarizing practical experiences and providing valuable insights for the ...
Xingyu Ming, Han Wei, Die Zhou, Jinyuan Tao, Bangfu Qian, Hongying Li, Jinliang Hu   +6 more
doaj   +1 more source

Epidemiological Profile of Oral Health Conditions in Ecuador: A Retrospective Study From 2016 to 2022

International Dental Journal
Introduction: The Global Action Plan on Oral Health 2023-2030 is reaffirmed, promoting prevention, equitable access, and affordability of essential oral healthcare, aligned with universal health coverage and addressing social and commercial determinants ...
C.M. Cecilia Belén Molina Jaramillo, W.B. Willy Bustillos Torrez, C.H. Christian Patricio Hernández Carrera, A.G. Ana Patricia Gutiérrez, D.L. Darwin Vicente Luna-Chonata   +4 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source