Results 71 to 80 of about 288,287 (260)

Pneumonia Hospitalization Coding Changes Associated With Transition From the 9th to 10th Revision of

Health Services Research & Managerial Epidemiology, 2020
Objectives: To evaluate the impact of International Classification of Disease , 10th revision, Clinical Modification ( ICD-10-CM ) implementation on pneumonia hospitalizations rates, which had declined following pneumococcal conjugate vaccine ...
Ryan B. Smithee, Tiffanie M. Markus, Elizabeth Soda, Carlos G. Grijalva, Wei Xing, Nong Shang, Marie R. Griffin, Fernanda C. Lessa   +7 more
doaj   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Help, my rating looks bad! Coding comorbidities in arthroplasty

Arthroplasty Today, 2016
In medicine today, there is a trend toward increasing transparency. Higher quality and better value are being sought, and one of the methods being used is publicly reported health care outcomes.
Joseph D. Galloway, MD, Frank R. Voss, MD   +1 more
doaj   +1 more source

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Coding rules for uncertain and “ruled out” diagnoses in ICD-10 and ICD-11

BMC Medical Informatics and Decision Making
The International Classification of Diseases, 11th Revision (ICD-11) has significantly improved the ability to navigate coding challenges beyond prior iterations of the ICD.
Oluseun O. Atolagbe, Patrick S. Romano, Danielle A. Southern, Wachira Wongtanasarasin, William A. Ghali   +4 more
doaj   +1 more source

Comparison of Diagnosis Codes to Clinical Notes in Classifying Patients with Diabetic Retinopathy

Ophthalmology Science
Purpose: Electronic health records (EHRs) contain a vast amount of clinical data. Improved automated classification approaches have the potential to accurately and efficiently identify patient cohorts for research.
Sean Yonamine, MPH, Chu Jian Ma, MD, PhD, Rolake O. Alabi, MD, PhD, Georgia Kaidonis, MBBS, PhD, Lawrence Chan, MD, Durga Borkar, MD, Joshua D. Stein, MD, MS, Benjamin F. Arnold, PhD, Catherine Q. Sun, MD   +8 more
doaj   +1 more source

Light‐Activatable Nitric Oxide Release via Intramolecular Electron Transfer for Tumor Pyroptosis Induction

Advanced Science, EarlyView.
This work proposes a novel strategy to fabricate unimolecular pyroptosis photoinitiators activated by deep‐red light at low light doses. It relies on a photosensitization mechanism to trigger nitric oxide (NO) release from benzisothiadiazole‐based N‐nitrosanilines without modification of nitro moieties, thereby boosting pyroptosis‐mediated ...
Chuangxin Zhang, Ruipeng Li, Yunxia Wang, Feng Liu, Liheng Feng   +4 more
wiley   +1 more source

Procedure coding in the American Joint Replacement Registry

Arthroplasty Today, 2019
In October 2015, the Centers for Medicare & Medicaid Services transitioned from the 9th version of the International Classification of Diseases (ICD-9) codes for reporting patient diagnosis and medical procedures to the 10th version (ICD-10).
September R. Cahue, MPH, Caryn D. Etkin, PhD, MPH, Louis S. Stryker, MD, Frank R. Voss, MD   +3 more
doaj   +1 more source