Results 121 to 130 of about 662,315 (337)

Three‐Dimensional Ovary Model to Improve and Study Murine Follicle Growth

open access: yesAdvanced Healthcare Materials, EarlyView.
To develop new methods for fertility preservation in women, novel culture systems for small follicles need to be established. In this work, a poly(ethylene glycol) based scaffold, with appropriate mechanical and bioactive features to support mouse follicle and ovary cell growth is developed, and the formed cell‐follicle interactions are visualized ...
Mira Jacobs   +6 more
wiley   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

open access: yesAdvanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani   +7 more
wiley   +1 more source

Response of Atlantic overturning to future warming in a coupled atmosphere‐ocean‐ice sheet model

open access: yes, 2015
Climate change can influence sea surface conditions and the melting rates of ice sheets; resulting in decreased deep water formation rates and ultimately affecting the strength of the Atlantic Meridional Overturning Circulation (AMOC).
P. Gierz, Gerrit Lohmann, Wei Wei
semanticscholar   +1 more source

Hydraulic impacts of glacier advance over a sediment bed [PDF]

open access: yes, 2006
A sedimentary sequence of till overlying a gravel aquifer was instrumented with water-pressure transducers prior to a small, anticipated surge of the margin of the glacier Breiðamerkurjökull in Iceland.
Baker   +14 more
core   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

open access: yesAdvanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong   +4 more
wiley   +1 more source

Physicochemical Reinforcement Unlocks Sterilization‐Stable Anisotropic Hydrogels for Cell‐Compatible Mock Arteries

open access: yesAdvanced Healthcare Materials, EarlyView.
ABSTRACT In vitro arterial models offer ethical and robust alternatives for vascular research but require cytocompatible materials that replicate physiological mechanics. Poly(vinyl alcohol) (PVA) hydrogels produced by directional freezing and salting‐out (PVA DFSO) are anisotropic yet lack stability for cell culture. Herein, methacrylated PVA (PVA‐MA)
Javiera Sanhueza Ortega   +4 more
wiley   +1 more source

Assessment of sub-shelf melting parameterisations using the ocean–ice-sheet coupled model NEMO(v3.6)–Elmer/Ice(v8.3)

open access: yesGeoscientific Model Development, 2019
. Oceanic melting beneath ice shelves is the main driver of the current mass loss of the Antarctic ice sheet and is mostly parameterised in stand-alone ice-sheet modelling.
L. Favier   +7 more
semanticscholar   +1 more source

Response of a zonal climate-ice sheet model to the orbital perturbations during the Quaternary ice ages [PDF]

open access: yes, 1980
The astronomical theory of the ice ages is investigated using a simple climate model which includes the ice sheets explicitly. A one-level, zonally averaged, seasonal energy-balance equation is solved numerically for sea-level temperature T as a function
Ingersoll, Andrew P.   +2 more
core   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

open access: yesAdvanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee   +8 more
wiley   +1 more source

Capabilities and performance of Elmer/Ice, a new-generation ice sheet model

open access: yes, 2013
The Fourth IPCC Assessment Report concluded that ice sheet flow models, in their current state, were unable to provide accurate forecast for the increase of polar ice sheet discharge and the associated contribution to sea level rise.
O. Gagliardini   +14 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy