Results 161 to 170 of about 3,902,696 (360)

Are X-rays the key to integrated computational materials engineering?

IUCrJ, 2015
Gene Ice
doaj   +1 more source

Projected land ice contributions to twenty-first-century sea level rise

Nature, 2021
T. Edwards, S. Nowicki, B. Marzeion, R. Hock, H. Goelzer, H. Seroussi, N. Jourdain, D. Slater, Fiona E. Turner, Christopher J. Smith, C. McKenna, E. Simon, A. Abe‐Ouchi, J. Gregory, E. Larour, W. Lipscomb, A. Payne, A. Shepherd, Cécile Agosta, P. Alexander, T. Albrecht, B. Anderson, X. Asay-Davis, A. Aschwanden, A. Barthel, A. Bliss, R. Calov, C. Chambers, N. Champollion, Youngmin Choi, R. Cullather, J. Cuzzone, C. Dumas, D. Felikson, X. Fettweis, K. Fujita, B. Galton-Fenzi, R. Gladstone, N. Golledge, R. Greve, T. Hattermann, M. Hoffman, A. Humbert, M. Huss, P. Huybrechts, W. Immerzeel, T. Kleiner, P. Kraaijenbrink, Sébastien Le clec’h, V. Lee, G. Leguy, C. Little, D. Lowry, J. Malles, Daniel F. Martin, F. Maussion, Mathieu Morlighem, James F. O'Neill, I. Nias, F. Pattyn, T. Pelle, S. Price, A. Quiquet, V. Radic, R. Reese, D. Rounce, M. Rückamp, A. Sakai, C. Shafer, N. Schlegel, S. Shannon, Robin S. Smith, F. Straneo, Sainan Sun, L. Tarasov, L. Trusel, Jonas Van Breedam, R. V. D. van de Wal, M. R. van den Broeke, R. Winkelmann, H. Zekollari, Chen Zhao, Tong Zhang, T. Zwinger   +83 more
semanticscholar   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

A nuclear magnetic resonance investigation of brine inclusions in Antarctic and artificial sea ice : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Science in Physics at Massey University [PDF]

, 2000
Additional images with the print copy held in the library.The aim of this thesis is to use Nuclear Magnetic Resonance (NMR) techniques to examine the brine pockets in sea ice. Both the movement of the brine pockets within the ice, and the movement of the
Furkert, Suzanne Alice
core  

Ice ice maybe [PDF]

Nature Chemistry, 2010
openaire   +2 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

The complete genome sequence of unculturable Mycoplasma faucium obtained through clinical metagenomic next-generation sequencing

Frontiers in Cellular and Infection Microbiology
IntroductionDiagnosing Mycoplasma faucium poses challenges, and it's unclear if its rare isolation is due to infrequent occurrence or its fastidious nutritional requirements.MethodsThis study analyzes the complete genome sequence of M.
Artur J. Sabat, Tim Durfee, Schuyler Baldwin, Viktoria Akkerboom, Andreas Voss, Alexander W. Friedrich, Erik Bathoorn   +6 more
doaj   +1 more source

Global analyses of sea surface temperature, sea ice, and night marine air temperature since the late nineteenth century

, 2003
N. Rayner, D. Parker, E. B. Horton, C. Folland, L. Alexander, D. Rowell, Elizabeth C. Kent, A. Kaplan   +7 more
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source