Results 141 to 150 of about 553,476 (284)

SlATG8f modulates tomato thermotolerance and fruit quality, correlating with changes in autophagy and heat shock-related genes. [PDF]

PLoS One
Cheng Q, Xu W, Wen C, He Z, Song L.
europepmc   +1 more source

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

Advanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim, Ha Kyeong Lee, Zulfikar Azam, Jeong Uk Choi, Riajul Wahab, Na Kyeong Lee, Yoon Gun Ko, So‐Young Choi, Se‐Ra Lee, Wan Seob Shim, Taeeung Kim, In‐San Kim, Farzana Alam, Sang Yoon Kim, Seong Who Kim, Youngro Byun, Taslim A Al‐Hilal   +16 more
wiley   +1 more source

A <i>Mycobacterium tuberculosis</i> Mbox controls a conserved, small upstream ORF via a translational expression platform and Rho-dependent termination of transcription. [PDF]

RNA
D'Halluin A, Kipkorir T, Hubert C, Barker D, Arnvig KB.   +4 more
europepmc   +1 more source

Divergent Regulatory Effects of Jasmonic Acid on Tomato Lycopene Biosynthesis Under Light and Dark Conditions

Advanced Science, EarlyView.
This study reveals the mechanism by which jasmonic acid (JA) regulates lycopene synthesis under light and dark conditions. In light, JA activates SlMYC2, which suppresses SlPIF1a and promotes SlPSY1 expression. In darkness, JA induces the acetyltransferase SlNATA1, which acetylates the dark‐accumulated SlPIF1a, thereby repressing SlPSY1 expression ...
Jiayi Xu, Lingfeng He, Jialong Zhang, Hao Cui, Hongxin Li, Haijun Zhang, Jiaojiao Zhang, Lun Liu, Kunpeng Xu, Yang‐Dong Guo, Na Zhang   +10 more
wiley   +1 more source

Transcriptome reveals differential expression of flavor and color in closely related strains of tomato (<i>Solanum lycopersicum</i>). [PDF]

PeerJ
Guo C, Liu X, Ding Y, He Z, Shi S, Ding Y, Shen H, Yang Z.   +7 more
europepmc   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Integrated transcriptomic and metabolomic analyses elucidate the regulatory role of SlBEL11 in tomato fruit ripening. [PDF]

Front Plant Sci
Dong X, Lu J, Guo Y, Zhang Q, Yang Q, Peng J, Tian L.   +6 more
europepmc   +1 more source

Which shape will make the best ice breaker?

Future Science OA, 2018
Noah Agbalaya, Obed Agyei, Ifrah Ahmed, Safan Abbasi, A. Atanasov, Cameron Burke-Shaw, Joel Bruno Santos da Costa, Kelsey Durrand, M. Faisal, S. Georgieva, Florence Hancock, Tyler Hargreaves, M. Hussain, Qaaim Hussain, Daniel Kajo, Yoana Karova, K. Kazi, A. Q. Khan, K. Knapek, Asia'h Lake, S. Majewski, S. Malcolm, M. Molu, Darren Owusu-Sekyere, Manav Parmar, M. Riaz, Tayba Shanji, Leasha Thomas-Daye, A. Wenda, M. Yahya   +29 more
semanticscholar   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Near-peer mentorship as a welcome ritual: exploring the what and how of McGill's "Buddy program". [PDF]

Can Med Educ J
Moussa S, Islam N, Datta A, Hassan A, Hassan A.   +4 more
europepmc   +1 more source