Results 111 to 120 of about 740,577 (309)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

ANNOTATED BIBLIOGRAPHY OF RUSSIAN LITERATURE ON GLACIOLOGY IN 2010

open access: yesЛëд и снег, 2015
This bibliography includes 294 books and articles published mostly in 2010. Annotated books and articles relate to ten thematic sections of glaciology:1. General problems of glaciology2. Physics and chemistry of ice3. Ice in atmosphere4.
V. M. Kotlyakov   +2 more
doaj   +1 more source

Studies of stratospheric particulates [PDF]

open access: yes
A sophisticated computer model of polar stratospheric clouds was developed and used to study the properties of ice clouds. The model has recently been extended to investigate nitric acid clouds and ice clouds as well as their interactions with ...
Hamill, Patrick   +3 more
core   +1 more source

The physics and chemistry of ice [PDF]

open access: yesPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2019
Thorsten Bartels-Rausch   +1 more
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Optimized step size control within the Rosenbrock solvers for stiff chemical ordinary differential equation systems in KPP version 2.2.3_rs4 [PDF]

open access: yesGeoscientific Model Development
Numerical integration of multiphase chemical kinetics in atmospheric models is challenging. The underlying system of ordinary differential equations (ODEs) is stiff and thus difficult to solve.
R. Dreger   +7 more
doaj   +1 more source

11.0.A Daily Outline [PDF]

open access: yes, 2016
WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core   +1 more source

Ice origins of OCS and chemistry of CS2-bearing ice mantles

open access: yesMonthly Notices of the Royal Astronomical Society
ABSTRACT Understanding the formation of carbonyl sulfide (OCS) in interstellar ices is key to constrain the sulfur chemistry in the interstellar medium (ISM), since it is the only ice S-bearing molecule securely detected thus far. Two general pathways for OCS formation have been proposed: sulfurization of CO (CO + S) and oxidation of CS (
Martín-Doménech, Rafael   +5 more
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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