Results 131 to 140 of about 804,547 (290)

Ice crystal icing in gas turbine engines

open access: yes, 2019
High altitude ice particles can accrete inside the core compression system of turbofan engines in cruise and descent. This can lead to severe in-flight events including blade damage, surge and flameout. This thesis describes the development and validation of a new comprehensive computational model to aid prediction of ice crystal icing in turbofan ...
openaire   +1 more source

Use of LANDSAT data for river and lake ice engineering studies [PDF]

open access: yes
There are no author-identified significant results in this ...
Hall, D. K.
core   +1 more source

GeoTechnical Investigations for the Dalton Highway Innovation Project As A Case Study of the Ice-Rich Syngenetic Permafrost [PDF]

open access: yes, 2010
INE/AUTC 11 ...
Dillon, Matthew   +4 more
core  

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Experimental Heat Transfer Supporting Simulated Water Well Performance on Mars [PDF]

open access: yes
Favorable indications of massive quantities of water on Mars have initiated studies of potential changes to human Mars missions. Using a technique known as a Rodriguez Well to melt the ice, store the resulting water in a subsurface ice cavity until ...
Andrews, Alida D.   +3 more
core   +1 more source

Prototyping Formal System Models with Active Objects

open access: yes, 2018
We propose active object languages as a development tool for formal system models of distributed systems. Additionally to a formalization based on a term rewriting system, we use established Software Engineering concepts, including software product lines
Hähnle, Reiner, Kamburjan, Eduard
core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Preparing for a Northwest Passage: A Workshop on the Role of New England in Navigating the New Arctic [PDF]

open access: yes, 2018
Preparing for a Northwest Passage: A Workshop on the Role of New England in Navigating the New Arctic (March 25 - 27, 2018 -- The University of New Hampshire) paired two of NSF\u27s 10 Big Ideas: Navigating the New Arctic and Growing Convergence ...
Ashcraft, Catherine M   +13 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

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