Results 91 to 100 of about 996,477 (244)

First description of subglacial megalineations from the late Paleozoic ice age in southern Africa.

PLoS ONE, 2019
We identify late Paleozoic ice age (LPIA) subglacial megalineations from field and geospatial imagery of the Twyfelfontein area of northern Namibia, and present the results of a geomorphometric analysis of those data.
Graham D Andrews, Andrew T McGrady, Sarah R Brown, Shannon M Maynard   +3 more
doaj   +1 more source

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

Advanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan, Youdan Zhang, Zhujun Wang, Huatao Tang, Huiping Liu, Zi Chen, Shuai Liu, Jiayi Shi, Lu Peng, Youming Hou   +9 more
wiley   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

Advanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai, Xin Mei Zhang, Jing Cheng Zhang, Xu Ting Deng, Qiao Liu, Mustafa Hussein Ali, Fang Zhou Yin, Wu Yin   +7 more
wiley   +1 more source

Adaptive Conductive Systems: Enabling Deformable Electronics Through Engineered Materials, Circuits, and Intelligent Systems

Advanced Science, EarlyView.
This review presents the research advances of adaptive conductive systems from the perspective of materials, circuits, systems, and applications. Deformable conductors consist of substrates/matrices and conductive materials, structural design of circuit interconnections, fabrication of circuit interconnections, as well as intelligent systems ...
Yufei Lu, Siyu Liang, Jingyi Niu, Jie Chen, Shuo Zhang, Hongjian Zhang, Dongsheng Jia, Wei Huang   +7 more
wiley   +1 more source

InSAR observations of ice elevation and velocity fluctuations at the Flade Isblink ice cap, eastern North Greenland [PDF]

, 2010
The 8500 km(2) Flade Isblink ice cap (FIIC) (81 degrees 15'N, 15 degrees 0'W) is the largest ice cap in Greenland. We use repeat-pass interferometric synthetic aperture radar (InSAR) techniques to investigate the form and flow of the FIIC.
Rinnem, Eero, Nienow, Peter, Peter Nienow, Andrew Shepherd, Palmer, Steven J., Shepherd, Andrew, Eero Rinnem, Aud Sundal, Sundal, Aud, Steven J. Palmer   +9 more
core   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

Advanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa, Rikuto Kawakami, Kunanon Chattrairat, Tatsuya Niwa, Taiga Ajiri, Takao Yasui, Masayoshi Tanaka   +6 more
wiley   +1 more source

Accelerating ice flow at the onset of the Northeast Greenland Ice Stream. [PDF]

Nat Commun, 2022
Grinsted A, Hvidberg CS, Lilien DA, Rathmann NM, Karlsson NB, Gerber T, Kjær HA, Vallelonga P, Dahl-Jensen D.   +8 more
europepmc   +1 more source

Self‐Sustaining Sensing Systems: Integration Strategies and Signal–Power Matching in Energy‐Harvesting Electronics

Advanced Science, EarlyView.
Energy‐harvesting‐integrated sensors couple ambient energy conversion with sensing, processing, and wireless communication. This review organizes recent progress through integration architectures and operating principles, revisiting co‐packaged, monolithic, and co‐functional designs together with always‐on, event‐driven, and multi‐modal sensing modes ...
Taehyun Park, Ki‐Yoon Park, Yeonho Choi, Dong‐Myeong Shin, Hong‐Joon Yoon, Hocheon Yoo   +5 more
wiley   +1 more source

An assessment of key model parametric uncertainties in projections of Greenland Ice Sheet behavior [PDF]

, 2012
Lack of knowledge about the values of ice sheet model input parameters introduces substantial uncertainty into projections of Greenland Ice Sheet contributions to future sea level rise.
Stone, Emma J., N. Kirchner, K. Keller, Keller, K., Greve, Ralf, Applegate, P. J., Greve, R., R. Greve, Keller, Klaus, Kirchner, N., Applegate, Patrick J.,, Applegate, Patrick J., Kirchner, Nina, Stone, EJ, Kirchner, Nina,, E. J. Stone, Stone, E. J., P. J. Applegate   +17 more
core   +2 more sources