Results 131 to 140 of about 464,025 (338)

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Influence of the Gulf Stream on the Barents Sea ice retreat and Eurasian coldness during early winter

Environmental Research Letters, 2014
Abnormal sea-ice retreat over the Barents Sea during early winter has been considered a leading driver of recent midlatitude severe winters over Eurasia. However, causal relationships between such retreat and the atmospheric circulation anomalies remains
Kazutoshi Sato, Jun Inoue, Masahiro Watanabe   +2 more
doaj   +1 more source

Trough geometry was a greater influence than climate-ocean forcing in regulating retreat of the marine-based Irish-Sea Ice Stream [PDF]

, 2018
David Small, Rachel Smedley, Richard C. Chiverrell, James Scourse, Colm Ó Cofaigh, G.A.T. Duller, Stephen McCarron, Matthew J. Burke, David J. A. Evans, Derek Fabel, Delia M. Gheorghiu, Geoff S.P. Thomas, Sheng Xu, Chris D. Clark   +13 more
openalex   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source

Ice-core insights into the flow and shut-down of Ice Stream C, West Antarctica [PDF]

, 2003
D. Voigt, Richard B. Alley, S. Anandakrishnan, Matthew K. Spencer   +3 more
openalex   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Thermal Weakening, Convergent Flow, and Vertical Heat Transport in the Northeast Greenland Ice Stream Shear Margins

Geophysical Research Letters, 2019
Ice streams are bounded by abrupt transitions in speed called shear margins. Some shear margins are fixed by subglacial topography, but others are thought to be self‐organizing, evolving by thermal feedback to ice viscosity and basal drag which govern ...
N. Holschuh, D. A. Lilien, K. Christianson   +2 more
doaj   +1 more source

A Modeling Experiment on the Grounding of an Ice Shelf in the Central Arctic Ocean During MIS 6 [PDF]

, 2003
High-resolution chirp sonar subbottom profiles from the Lomonosov Ridge in the central Arctic Ocean, acquired from the Swedish icebreaker Oden in 1996, revealed large-scale erosion of the ridge crest down to depths of 1000 m below present sea level ...
Jakobsson, Martin, Paton, Mark, Siegert, M   +2 more
core   +2 more sources

Durable Thin‐Film Porous Transport Electrodes for High Current Density PEM Water Electrolysis

Advanced Science, EarlyView.
Water electrolysis using porous transport electrodes with sputter‐deposited, ionomer‐free thin films of rutile IrO2 catalyst suppresses Ir dissolution by >10x over other forms of IrOx. The rutile IrO2 catalyst prepared by this readily scalable electrode synthesis method provides stable cell operation at 3 A cm−2 while using low Ir loading (0.4 mg Ir cm−
James L. Young, Diana E. Beltrán, Sarah J. Blair, Ricardo P. M. Duarte, Makenzie R. Parimuha, Haoran Yu, Lonneke van Eijk, Kimberly S. Reeves, Tomas Grejtak, Jorge Martinez, Bennett A. Chao, Jacob Wrubel, Melissa E. Kreider, Elisa M. Miller, Julia D. Lenef, Karen N. Heinselman, Svitlana Pylypenko, David A. Cullen, Guido Bender   +18 more
wiley   +1 more source

“Ice Streams” [PDF]

Polar Record, 1954
openaire   +2 more sources