Results 191 to 200 of about 1,337,857 (345)

Studies of the grounding-line location on Ice Streams D and E, Antarctica [PDF]

open access: bronze, 1994
R. W. Jacobel   +2 more
openalex   +1 more source

Ecologic and Economic Evaluation of Combined Methanol Synthesis from CO2 and Biotechnological Upgrading to Value Products. Part 1: Environmental Impact

open access: yesChemie Ingenieur Technik, EarlyView.
The combination of methanol synthesis and biotechnological upgrading to value‐added products still faces some challenges in order to achieve a positive environmental impact and thus the goal of synergetic development of biotechnological and chemical processes.
Mehran Taherkhani   +3 more
wiley   +1 more source

PALAEO-ICE STREAMS IN THE NORTH-EASTERN LAURENTIDE ICE SHEET

open access: yes, 2007
This thesis presents a palaeoglaciological study aimed to determine the location, geometry and temporal evolution of palaeo-ice streams of the north-easternmost Laurentide Ice Sheet. The work was accomplished through the geomorphological interpretation of satellite imagery over 3.19 x 106 km2 of the Canadian Arctic, using a glaciological inversion ...
openaire   +3 more sources

Actin Filament Pointed Ends: Assays for Regulation of Assembly and Disassembly by Tropomodulin and Tropomyosin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Actin filaments are dynamic polymers whose length depends on regulated monomer association and dissociation at their ends. Actin barbed‐end dynamics are relatively better understood, primarily due to the approximately tenfold faster subunit on/off rates at barbed versus pointed ends.
Sawako Yamashiro   +5 more
wiley   +1 more source

Novel Para‐Phenylenediamine‐Based Derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization

open access: yesChemMedChem, EarlyView.
ROR1 represents a promising target for the development of novel antiproliferative compounds, giving its high expression in different cancer cell lines. The present study describes the workflow leading to the design, synthesis, and characterization of a series of para‐phenylenediamine‐based compounds able to interact with the target kinase, inhibiting ...
Gerardina Smaldone   +17 more
wiley   +1 more source

Sustained ocean cooling insufficient to reverse sea level rise from Antarctica

open access: yesCommunications Earth & Environment
Global mean sea level has risen at an accelerating rate in the last decade and will continue to rise for centuries. The Amundsen Sea Embayment in West Antarctica is a critical region for present and future ice loss, however most studies consider only a ...
Alanna Alevropoulos-Borrill   +4 more
doaj   +1 more source

Inhibition of the clathrin terminal domain – amphiphysin protein‐protein interaction. Probing the Pitstop® 2 aromatic moiety.

open access: yesChemMedChem, Accepted Article.
Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)‐4‐oxo‐4,5‐dihydrothiazol‐2‐yl)naphthalene‐1‐sulfonamide (1), inhibits the clathrin terminal domain‐ amphiphysin interaction (NTD‐PPI) and has been widely used to investigate endocytosis. In this work we report on the synthesis of 56 novel Pitstop 2 analogues via four discrete focused libraries.
Kate Prichard   +10 more
wiley   +1 more source

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