Results 91 to 100 of about 6,950 (262)

Prevalence, Characteristics, and Outcomes of People With A High Body Mass Index Across the Kidney Disease Spectrum: A Population-Based Cohort Study

Canadian Journal of Kidney Health and Disease
Background: Obesity has a major impact on health and health care, particularly in those with chronic kidney disease (CKD). Objective: The objective was to describe the prevalence, characteristics, and outcomes of people living with CKD and obesity ...
Gurleen Sahi, Jennifer Reid, Louise Moist, Michael Chiu, Amanda Vinson, Saverio Stranges, Kyla Naylor, Yunxu Zhu, Kristin K. Clemens   +8 more
doaj   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

‘Horses for courses’ – an interrogation of tools for marine ecosystem-based management

Frontiers in Marine Science
Marine Ecosystem-Based Management (EBM) approaches are a well-established and fundamental component of international agreements and treaties, regional seas conventions, assessment strategies, European Directives and national and regional instruments ...
Nadia Papadopoulou, Christopher John Smith, Anita Franco, Michael Elliott, Michael Elliott, Angel Borja, Jesper H. Andersen, Jesper H. Andersen, Eva Amorim, Jon P. Atkins, Steve Barnard, Torsten Berg, Silvana N. R. Birchenough, Silvana N. R. Birchenough, Daryl Burdon, Joachim Claudet, Roland Cormier, Ibon Galparsoro, Adrian Judd, Stelios Katsanevakis, Samuli Korpinen, Luminita Lazar, Charles Loiseau, Christopher Lynam, Iratxe Menchaca, Christina O’Toole, Debbi Pedreschi, Gerjan Piet, Dave Reid, Dave Reid, Irene Antonina Salinas-Akhmadeeva, Vanessa Stelzenmüller, Jacqueline E. Tamis, Laura Uusitalo, Laura Uusitalo, Maria C. Uyarra   +35 more
doaj   +1 more source

Resonant Domain Wall Dynamics in a Three‐Dimensional Magnetic Nano Double Helix

Advanced Materials, EarlyView.
3D magnetic nanostructures promise exciting possibilities for magnetization dynamics. However, experimental realizations remain scarce. In nanoprinted cobalt double helices, time‐resolved X‐ray microscopy reveals harmonic domain wall dynamics. Simulations identify the mode and additional higher‐frequency resonances, revealing a rich dynamic landscape ...
Pamela Morales‐Fernández, Iason Konstantinos‐Douveas, Claas Abert, Elina Zhakina, Sandra Ruiz‐Gómez, Claudia Fernández‐González, Luke Alexander Turnbull, Sebastian Wintz, Markus König, Simone Finizio, Markus Weigand, Naëmi Leo, Dieter Suess, Aurelio Hierro‐Rodríguez, Amalio Fernández‐Pacheco, Claire Donnelly   +15 more
wiley   +1 more source

Boolean Logic‐Based Control Over Recombinant Protein Biomaterial Degradability and Therapeutic Delivery

Advanced Materials, EarlyView.
Fully recombinant protein‐based biomaterials execute complex Boolean logic for user‐programmable material degradation and concomitant therapeutic cargo release. Biologics, such as growth factors, can be incorporated within the crosslinkers as “drugamers”, while encapsulated cells can be released according to nested YES/OR/AND‐type logical operations ...
Murial L. Ross, Ryan Gharios, Shivani Kottantharayil, Cole A. DeForest   +3 more
wiley   +1 more source

Mechanistically Interpretable Artificial Intelligence for Designing Oxygen Electrocatalysts

Advanced Materials, EarlyView.
Mechanistically interpretable artificial intelligence screens nearly seven million perovskite compositions and identifies key descriptors—d‐p hybridization and densification resistance—that govern oxygen electrocatalysis. The discovered BaCo0.8Nb0.1Zr0.1O3‐δ achieves a record 2.68 W cm−2 peak power density at 600°C with over 500 h of durable operation ...
Xueyu Hu, Yucun Zhou, Haoyu Li, Zheyu Luo, Nai Shi, Yong Ding, Weining Wang, Weilin Zhang, Doyeub Kim, Chanho Kim, Yoojin Ahn, Nikhil Govindarajan, Minda Zou, Zhijun Liu, Yuefeng Song, Meilin Liu   +15 more
wiley   +1 more source

Sustainable and Multifunctional Natural Macromolecular Polymers for Aqueous Zn Metal Batteries

Advanced Materials, EarlyView.
We comprehensively review the structure‐function relationships and regulatory mechanism of natural macromolecular polymers in stabilizing zinc anodes at the microscopic and mesoscopic scales. The interactions among polymer structures, optimization strategies, and regulatory mechanisms are discussed systematically summarizing recent related research ...
Yunuo Shi, Bo Jiang, Jingcheng Zhang, Xiaodong Shao, Peixun Xiong, Lutong Shan, Shengyang Huang, Mengfang Liang, Mengyao Chang, Fangyan Liu, Wenwu Li, Baoyu Xia, Wei Ji, Ho Seok Park   +13 more
wiley   +1 more source

FISHGLOB: A collaborative infrastructure to bridge the gap between scientific monitoring and marine biodiversity conservation

Conservation Science and Practice
Large‐scale biodiversity assessments and conservation applications require integrated and up‐to‐date datasets across regions. In the oceans, monitoring is fragmented, which affects knowledge exchange and usage.
Aurore A. Maureaud, Zoë Kitchel, Alexa Fredston, Robert Guralnick, Juliano Palacios‐Abrantes, Maria L. D. Palomares, Malin L. Pinsky, Nancy L. Shackell, James T. Thorson, Daniela Alemany, Kofi Amador, Rathnayaka Mudiyanselage Wajra Jeewantha Bandara, Jonathan Belmaker, Esther D. Beukhof, Steven J. Bograd, Mohamed Lamine Camara, Pierluigi Carbonara, Shahar Chaikin, Martin A. Collins, Tyler D. Eddy, Dori Edelist, Heino O. Fock, Romain Frelat, Kevin Friedland, Arnaud Grüss, Manuel Hidalgo, Didier Jouffre, Saïkou Oumar Kidé, Mariano Koen‐Alonso, Ian Knuckey, Stan Kotwicki, Edward Lavender, Martin Lindegren, Marcos Llope, Laura Mannocci, Julia G. Mason, Hicham Masski, Matthew McLean, Laurène Merillet, Vesselina Mihneva, Francis K. E. Nunoo, Richard L. O'Driscoll, Cecilia O'Leary, Laurene Pecuchet, Elitsa Petrova, Jorge E. Ramos, Ignacio Sobrino, Jón Sólmundsson, Vaishav Soni, Ingrid Spies, Maria Teresa Spedicato, Fabrice Stephenson, Ndiaga Thiam, Feriha Tserkova, George Tserpes, Evangelos Tzanatos, Daniël vanDenderen, Paraskevas Vasilakopoulos, Tom Webb, Daniela V. Yepsen, Philippe Ziegler, Walter Zupa, Bastien Mérigot   +62 more
doaj   +1 more source

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source