Results 121 to 130 of about 6,950 (262)

Validation of a health administrative definition of obstructive sleep apnea in children in Ontario, Canada. [PDF]

PLoS One
Radhakrishnan D, Kendzerska T, Katz S, Blinder H, Bin Hasan S, Naik T, Benchimol E, Narang I, Al-Saleh S.   +8 more
europepmc   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

The association between patient preferred language and end-of-life outcomes of home care patients who died from a cancer in Ontario, Canada - A retrospective cohort study. [PDF]

PLoS One
Wang TF, Bjerre LM, Gibb M, Yoo S, Pugliese M, Kim W, Moledina A, Engel FD, Lominy W, Carrier M, Tanuseputro P, Johnston S, Backman C.   +12 more
europepmc   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

Evidence of transfer of antimicrobial resistance genes from the porcine pathogen <i>Streptococcus suis</i> to human clinical isolates of <i>Streptococcus agalactiae</i> in a major pig-producing region of Spain. [PDF]

One Health
Uruén C, Lavilla MJ, Libante V, Marín CM, Rezusta A, Payot S, Arenas J.   +6 more
europepmc   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Geographic variation and neighbourhood correlates of mental health-related hospitalizations and emergency department visits in children and youth during the COVID-19 pandemic: a population-based study. [PDF]

Front Child Adolesc Psychiatry
Antoniou T, Gozdyra P, Fridman D, Pajer K, Gomes T, Penner M, Tadrous M, Juurlink DN, Gardner W.   +8 more
europepmc   +1 more source

SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening

Advanced Science, EarlyView.
Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen, Jiaqi Yu, Jing Xu, Lingqi Chen, Ninghao Zhang, Wenrui Li, Runmin Zeng, Xiaomin Luo, Yiqun Chang, Jiayin Lai, Wenshi Huang, Xiaochen Liang, Ting Zhao, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Xueqin Huang, Haibo Zhou, Junxia Zheng   +20 more
wiley   +1 more source

Non-equilibrium preparation of (<i>E</i>)-phosphinimine (HPNH, X¹A') - a precursor to prebiotic phosphorylating agents. [PDF]

Chem Sci
Wang J, Sun BJ, Bergantini A, Wang Z, McAnally M, Marks JH, Chang AHH, Eckhardt AK, Kaiser RI.   +8 more
europepmc   +1 more source

Polar Ice as an Unconventional Water Resource: Opportunities and Challenges

, 2021
Torabi Haghighi Ali, Klöve Björn, Karimidastenaei Zahra   +2 more
openaire   +1 more source