Results 191 to 200 of about 53,932 (284)

Phase 1 Study of Safety and PK With A Combination of Omeprazole and Trimetazidine for Fatty Acid Oxidation Inhibition in Patients With Advanced Solid Tumors

Clinical and Translational Science, Volume 19, Issue 11, November 2026.
ABSTRACT Fatty acid oxidation (FAO) is a metabolic vulnerability in cancer cells, making pharmacologic FAO inhibition a promising therapeutic strategy. This Phase I, open‐label, 3 + 3 dose‐escalation study evaluated the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of two oral FAO inhibitors—omeprazole (KN510), a carnitine ...
Wonyoung Choi, Jung W. Chun, Sung H. Sim, Sung‐Sik Han, Woo J. Lee, Joon H. Kang, Hyun Chul Kim, SeungHwan Lee, Jun H. Lee, Hyun J. Yoo, Soo‐Youl Kim, Sang M. Woo   +11 more
wiley   +1 more source

Circulating extracellular vesicles-microRNAs as potential biomarkers for the identification of ME/CFS: differentiating fatigue-related conditions. [PDF]

J Transl Med
Eguchi A, Kuratsune H, Nakatomi Y, Yasui T, Nakagawa R, Watanabe Y, Fukuda S.   +6 more
europepmc   +1 more source

The F‐words for childhood development in community‐based physical activity programmes for children with physical disabilities: A scoping review

Developmental Medicine &Child Neurology, Volume 68, Issue 11, Page 1501-1513, November 2026.
This scoping review identifies intervention ingredients that address the F‐words for childhood development in community‐based physical activity programs for children with physical disabilities. An electronic database and hand search of the international literature was conducted.
Belinda Munroe, Sarah Ashcroft, Suzanne Lock, Kylie Turner, Belinda Arnold, Sarah Reedman   +5 more
wiley   +1 more source

Living with diabetes in the Brazilian Amazon: Exploring barriers and supports for healthy lifestyle practices

Diabetic Medicine, Volume 43, Issue 11, November 2026.
Abstract Aims To investigate the barriers and facilitators to adopting healthy lifestyle habits among patients with type 2 diabetes mellitus (T2DM) in the Brazilian Amazon, using the Environmental Factors domain of the International Classification of Functioning, Disability and Health (ICF) as a conceptual framework.
Thalyta Mariany Rêgo Lopes Ueno, Tiago Assunção dos Santos Farias, Wagner Ferreira Monteiro, Maria Paula dos Santos, Hércules Lázaro Morais Campos, Elisa Brosina de Leon   +5 more
wiley   +1 more source

Importance of Comprehensive Tinnitus Assessment: A Conceptual Analysis of International Classification of Functioning, Disability and Health (ICF)-Linked Questionnaires. [PDF]

J Audiol Otol
Naudé A, Kanji A.
europepmc   +1 more source

Development and Psychometric Assessment of a Measurement Instrument for Functioning and Function-Affecting Factors in Women With Breast Cancer: A Rasch Analysis Approach. [PDF]

J Eval Clin Pract
Jamshidihosseinabadi F, Farzad M, Bakhshi E, Hosseini SA, Emami AH, Roudini K, Mirzania M, Shahi F, Esfandbod M, Asgarabad MH.   +9 more
europepmc   +1 more source

Ageing in Adults With Mild and Moderate Intellectual Disabilities in Brazil: A Biopsychosocial Comparison of Individuals With and Without Down Syndrome

Journal of Intellectual Disability Research, Volume 70, Issue 11, Page 1192-1202, November 2026.
ABSTRACT Objectives The objective of this study is to investigate functional, cognitive, physical and nutritional outcomes in adults with intellectual disabilities (IDs), comparing individuals with and without Down syndrome from São Paulo, Brazil, and to evaluate the associations of group, degree of disability, age and sex with these outcomes ...
Leila Regina de Castro, Rita de Cassia Ernandes, Erika Christina Gouveia e Silva, Luciana Mascarenhas Fonseca, José Maria Montiel, Angelica Castilho Alonso   +5 more
wiley   +1 more source

Linking the Pre-Assessment Information Form (PIF) to the ICF: Enhancing Standardized Functional Assessment in Parkinson's Disease. [PDF]

Physiother Res Int
Rogatto FBT, Guelfi ÉTN, Alflen VEV, Silva LBB, Pereira GS, Silva SM.   +5 more
europepmc   +1 more source

Asymmetric Migration Shapes Genetic Structure of the Invasive Avian Vampire Fly (Philornis downsi) Across the Galápagos Islands

Molecular Ecology, Volume 35, Issue 21, November 2026.
ABSTRACT Biological invasions on islands provide a natural framework to study how dispersal and connectivity influence evolutionary and ecological processes. The avian nest parasitic fly, Philornis downsi—first recorded in Darwin's finch nests in 1997—causes high mortality in endemic land birds, yet its inter‐island and sex‐specific patterns of ...
Abbie C. Hay, Sonia Kleindorfer, Lauren K. Common, Sally Potter, Jennifer A. H. Koop, George E. Heimpel, Sarah A. Knutie, Birgit Fessl, Lorraine Pérez‐Beauchamp, Rachael Y. Dudaniec   +9 more
wiley   +1 more source