Results 51 to 60 of about 163,685 (313)

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Impact of heating temperatures on the properties of instant cassava flour

Czech Journal of Food Sciences, 2021
Native cassava flour can be modified to be instant flour by heating the cassava flour in ethanol solution. The impact of heating temperatures of 60, 80, and 100 °C (coded as ICF-60, ICF-80, and ICF-100) on the properties of instant cassava flour (ICF ...
Achmat Sarifudin, Enny Sholichah, Woro Setiaboma, Nok Afifah, Dewi Desnilasari, Khairul Amri, Sunanta Tongta   +6 more
doaj   +1 more source

The Primordial Helium Abundance: Towards Understanding and Removing the Cosmic Scatter in the dY/dZ Relation [PDF]

, 2000
We present results from photoionization models of low-metallicity HII regions. These nebulae form the basis for measuring the primordial helium abundance.
Bottorf M., D. R. Ballantyne, G. J. Ferland, Netzer H., P. G. Martin, Pagel B. E. J., Peimbert M., Schaerer D., Schaerer D., Skillman E. D., Stasinska G., Stasinska G., Stasinska G., Stoy R. H.   +13 more
core   +4 more sources

Implementation of the International Classification of Functioning, Disability, and Health (ICF) Core Sets for Children and Youth with Cerebral Palsy: Global Initiatives Promoting Optimal Functioning

International Journal of Environmental Research and Public Health, 2018
Background: The International Classification of Functioning, Disability, and Health (ICF) Core Sets for children and youth with cerebral palsy (CP) offer service providers and stakeholders a specific framework to explore functioning and disability for ...
V. Schiariti, E. Longo, A. Shoshmin, L. Kozhushko, Y. Besstrashnova, M. Król, Taynah Neri Correia Campos, Haryelle Náryma Confessor Ferreira, C. Veríssimo, Daniel Shaba, Matilda Mwale, S. Amado   +11 more
semanticscholar   +1 more source

The 9th International RASopathies Symposium

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel, Lisa Schoyer, Beth Stronach, Raya Bogdanova, Anton M. Bennett, Jaishri Blakeley, Miriam Bornhorst, Tammy Bowers, Saskia M. Brachmann, Emma Burkitt‐Wright, Kathryn Chatfield, Alessandro De Luca, Khalil El‐Chammas, Abdul Elkadri, John E. Fortunato, Bruce D. Gelb, Anne Goriely, Karen Gripp, Kassidy Grover, Lindsay Homan, Kenneth A. Kern, Maija Kiuru, Charles (Chuck) Lawson, Yong‐Seok Lee, Frank McCormick, Gina Ney, Cristina Nuevo‐Tapioles, Sara Pardej, Elizabeth I. Pierpont, Julia Plank, Nancy Ratner, Katherine A. Rauen, J. Elliott Robinson, Les Rogers, Sarah E. Sheppard, Keir Shiels, David Stevenson, Dagmar Tiemens, Matthew Traylor, K. Nicole Weaver, Marielle Yohe, Tamar Green   +41 more
wiley   +1 more source

Integrating evidence in disability evaluation by social insurance physicians

Scandinavian Journal of Work, Environment & Health, 2011
OBJECTIVE: The aim of this study was to explore applying the method of evidence-based medicine (EBM) to resolve common questions in the field of disability evaluation.
Rob Kok, Jan L Hoving, Jos Verbeek, Frederieke G Schaafsma, Frank JH van Dijk   +4 more
doaj   +1 more source

Ionization Corrections For Low-Metallicity H II Regions and the Primordial Helium Abundance

, 1999
Helium and hydrogen recombination lines observed in low-metallicity, extragalactic H II regions provide the data used to infer the primordial helium mass fraction, Y_P.
Cid-Fernandes R., Gary Steigman, Levshakov S. A., Lopez R., Pagel B. E. J., Peimbert M., Peimbert M., Peimbert M., Peimbert M., Ruth Gruenwald, Stasinska G., Stasinska G., Sueli M. Viegas, Vilchez J. M.   +13 more
core   +3 more sources

What does the chronic pain grade questionnaire measure? [PDF]

, 2007
This study explored the ability of the Chronic Pain Grade Questionnaire (CPG) to operationalise the WHO's model of health outcomes, namely the International Classification of Functioning, Disability and Health (ICF).
Beth Pollard, Brockow, Cieza, Cieza, Cieza, Diane Dixon, Dreinhofer, Elliott, Finger, Hochberg, Johnston, Lynn, Marie Johnston, Pollard, Reed, Rubio, Steiner, Stucki, Vonkorff, Vonkorff, Weigl   +20 more
core   +1 more source

Hierarchical Complementary Enhanced Autoencoder Integrating Spatio‐Temporal Interaction Feature for Soft Sensor

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT To address the issues of neglecting the spatiotemporal correlations among process variables, low‐level features are vulnerable to noise interference, and the gradual loss of key information layer by layer during deep network training in traditional stacked autoencoder‐based soft‐sensor models, this paper proposes a hierarchical complementary ...
Xiaoping Guo, Jinghong Guo, Yuan Li
wiley   +1 more source

Acceptability of a smart lighter for tracking cigarette smoking: A focus group study

Digital Health
Background Smart lighters track cigarette smoking episodes, which can help identify smoking patterns and intervention approaches to promote cessation. We gauged the acceptability of smart lighters among individuals with low socioeconomic status (SES), a ...
Lydia Tesfaye, Michael Wakeman, Tim Gregory, Erin Leahy, Gunnar Baskin, Greg Gruse, Brandon Kendrick, Sherine El-Toukhy   +7 more
doaj   +1 more source