Results 41 to 50 of about 20,228 (287)

Agent-Based Models and Simulations in Economics and Social Sciences: from conceptual exploration to distinct ways of experimenting [PDF]

open access: yes, 2008
Now that complex Agent-Based Models and computer simulations spread over economics and social sciences - as in most sciences of complex systems -, epistemological puzzles (re)emerge. We introduce new epistemological tools so
Phan, Denis, Varenne, Franck
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Iconicity as Multimodal, Polysemiotic, and Plurifunctional

open access: yesFrontiers in Psychology, 2022
Investigations of iconicity in language, whereby interactants coordinate meaningful bodily actions to create resemblances, are prevalent across the human communication sciences. However, when it comes to analysing and comparing iconicity across different
Gabrielle Hodge   +2 more
doaj   +1 more source

Beyond the icon: Core cognition and the bounds of perception [PDF]

open access: yes, 2022
This paper refines a controversial proposal: that core systems belong to a perceptual kind, marked out by the format of its representational outputs.
Clarke, Sam
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Intersemiotic translation and transformational creativity [PDF]

open access: yes, 2015
In this article we approach a case of intersemiotic translation as a paradigmatic example of Boden’s ‘transformational creativity’ category. To develop our argument, we consider Boden’s fundamental notion of ‘conceptual space’ as a regular pattern of ...
Aguiar, Daniella   +2 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Ikoniczność: podobieństwo i „tertium comparationis"

open access: yesPrzestrzenie Teorii, 2007
The paper analyses the phenomenon of iconicity in relation to its significance for literary theory. One of the key notions in modern philosophy of language and linguistics, iconicity is seen as a motivated interrelation beween form and meaning.
Elżbieta Tabakowska
doaj   +1 more source

Symbiotic modeling: Linguistic Anthropology and the promise of chiasmus [PDF]

open access: yes, 2016
Reflexive observations and observations of reflexivity: such agendas are by now standard practice in anthropology. Dynamic feedback loops between self and other, cause and effect, represented and representamen may no longer seem surprising ...
Bartoli Cannada   +44 more
core   +1 more source

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