Results 51 to 60 of about 20,228 (287)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

The face and the faceness: Iconicity in the early faciasemiotics of Paul Ekman, 1957–1978

open access: yesSign Systems Studies, 2021
Paul Ekman is an American psychologist who pioneered the study of facial behaviour. Bringing together disciplinary history, life study, and history of science, this paper focuses on Ekman’s early research during the twenty-year period between 1957 and ...
Devon Schiller
doaj   +1 more source

Mapping language to the world: the role of iconicity in the sign language input [PDF]

open access: yes, 2017
Most research on the mechanisms underlying referential mapping has assumed that learning occurs in ostensive contexts, where label and referent co-occur, and that form and meaning are linked by arbitrary convention alone.
Lu, J.C.   +3 more
core   +4 more sources

Tuning the Dielectric Properties of Individual Clay Nanosheets by Interlayer Composition: Toward Nano‐Electret Materials

open access: yesAdvanced Functional Materials, EarlyView.
The dielectric properties of clays are studied on the level of individual monolayers and functional double stacks. The material breakdown characteristics and charge storage performance are analyzed. For illustration, a defined charge pattern representing a cuneiform character is produced, written into a microscopic clay tile, referencing the origins of
Sebastian Gödrich   +6 more
wiley   +1 more source

Sound Symbolism in Foreign Language Phonological Acquisition [PDF]

open access: yes, 2010
The paper aims at investigating the idea of a symbolic nature of sounds and its implications for in the acquisition of foreign language phonology. Firstly, it will present an overview of universal trends in phonetic symbolism, i.e.
Wrembel, Magdalena
core   +2 more sources

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

open access: yesAdvanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore   +7 more
wiley   +1 more source

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

open access: yesAdvanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen   +3 more
wiley   +1 more source

Woorde wat teken en be-teken – ikonisiteit in die poësie

open access: yesLiterator, 2008
Words as signs and signatures – iconicity in poetic texts In this article aspects of iconicity in language and in poetic texts are discussed. The recent renewed interest in the anti-arbitrary debate is used as a point of departure in order to examine ...
Heilna du Plooy
doaj   +1 more source

Motion iconicity in prosody

open access: yesFrontiers in Communication, 2022
Evidence suggests that human non-verbal speech may be rich in iconicity. Here, we report results from two experiments aimed at testing whether perception of increasing and declining f0 can be iconically mapped onto motion events. We presented a sample of
Axel G. Ekström   +3 more
doaj   +1 more source

Prototype effects in discourse and the synonymy issue: Two Lakota postpositions [PDF]

open access: yes, 2003
Despite of being fully synonymous at the semantic level, the postpositions el "locative/directional" and ekta "locative/directional" in Lakota (Siouan, Central North America) display different semantic cores in discourse: the semantic prototype for el is
Haiman   +5 more
core   +1 more source

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