Results 201 to 210 of about 117,111 (323)

From Diagnosis to Disease Staging: Multisite Validation of Cerebrospinal Fluid Molecular Tests in Multiple Sclerosis

Annals of Neurology, Volume 99, Issue 2, Page 328-340, February 2026.
Objective The growing demand for personalized treatment in multiple sclerosis (MS) highlights the need for more precise biomarkers that can outperform magnetic resonance imaging and clinical assessment in patient stratification. Advances in multiplex proteomic technologies suggest that cerebrospinal fluid (CSF) analysis at MS onset may not only improve
Laura Ghezzi, Peter Kosa, Mark Greenwood, Enrique Alvarez, C. L. Freedman, Anne H. Cross, Francesca Pace, Mark S. Freedman, Joanna Kocot, Laura Piccio, Bibiana Bielekova   +10 more
wiley   +1 more source

Amorphous-amorphous transitions in granular packings. [PDF]

Nat Commun
Yuan H, Kob W, Wang Y.
europepmc   +1 more source

Overcoming challenges in CAR‐T therapy for malignancies: Mechanisms and strategies

Clinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Chimeric antigen receptor T (CAR‐T) cell therapy faces three major challenges: tumour‐intrinsic resistance mechanisms, limitations in CAR‐T cell efficacy and immunosuppressive tumour microenvironment (TME) effects. Emerging strategies address these hurdles through precision targeting enhancement, optimised CAR‐T cell persistence/functionality and TME ...
Yushan Huang, Jun Long, Changpeng Yang, Wang Lu, Husheng Mei, Wenbin Qian, Jing Yang, Aibin Liang   +7 more
wiley   +1 more source

Enhanced ICOS Signaling Between Dendritic Cells and T Cells Characterizes the Immune Landscape of Human Cholangiocarcinoma. [PDF]

Hum Mutat
Zhu M, Li Y, Tang X, Wan X, Zhou Z.
europepmc   +1 more source

ICOS community

On-line Community customized for ICOS with set ...
openaire   +1 more source

The impact of B‐cell reconstitution on mRNA vaccine responses in allogeneic stem cell transplant recipients

Clinical &Translational Immunology, Volume 15, Issue 2, 2026.
We characterised B‐cell responses to vaccination in allogeneic haematopoietic stem cell transplant (alloHCT) recipients. While mRNA prime‐boost vaccination stimulated expansion of vaccine‐specific B cells to affinity mature in a majority of alloHCT recipients, responses were variable and seemingly restricted by the presence of immature B‐cell ...
Fredrika Hellgren, Rodrigo Arcoverde Cerveira, Gustaf Lindgren, Puran Chen, Klara Lenart, Sebastian Ols, Alberto Cagigi, Davide Valentini, Mireia Rocavert Barranco, Evangelin Shaloom Vitus, Martin Corcoran, Yong‐Dae Gwon, Mattias NE Forsell, Magnus Evander, COVAXID Study Group, Peter Bergman, Marcus Buggert, Hans‐Gustaf Ljunggren, Soo Aleman, Gunilla B Karlsson Hedestam, Andreas Björklund, Anna Nordlander, Per Ljungman, Stephan Mielke, Karin Loré   +24 more
wiley   +1 more source

Prognostic Performance of a Modified HFA-ICOS Tool for Prediction of Cardiovascular Complications in Cancer Patients. [PDF]

JACC Adv
Gynnild MN, Vinje-Jakobsen V, Holtrop J, Hageman SHJ, Holte E, Gulati G, Heck SL, Dorresteijn JAN, Visseren FLJ, Fagerli UM, Raj S, Dalen H, Omland T, Wethal T.   +13 more
europepmc   +1 more source

ICOS website

Description of the website.
openaire   +1 more source

T‐cell exhaustion from a multiomics perspective: Differentiation mechanisms and regulatory networks in the journey from progenitor‐Exhausted T cells to terminally exhausted T cells

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
(1) Core Process: Persistent antigen, from TDLNs to TME, drives Tpex → Tex‐int → Tex‐term differentiation. (2) Multiomics Regulation: This fate transition is orchestrated by a co‐ordinated, multi‐layered molecular network. (3) Functional Outcome: Dysregulated signalling and surging co‐inhibitory receptors lock in proliferative arrest and functional ...
Tong Zhu, Xiaoyu Teng, Qinlian Jiao, Yidan Ren, Yunshan Wang, Maoxiao Feng   +5 more
wiley   +1 more source

Function of follicular helper 17 T cells in driving B cells for anti-DNA autoantibody production in patients with SLE. [PDF]

Lupus Sci Med
Khunsri T, Tianpothong P, Kochayoo P, Thawornpan P, Suangtamai T, Leepiyasakulchai C, Ngamjanyaporn P, Pisitkun P, Chootong P.   +8 more
europepmc   +1 more source