Results 221 to 230 of about 117,111 (323)

IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura

open access: yesPediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak   +7 more
wiley   +1 more source

CST7<sup>+</sup> macrophages/monocytes in melanoma: single-cell insights into immunotherapy response. [PDF]

open access: yesTransl Cancer Res
Yao K   +9 more
europepmc   +1 more source

Antihypertensive Past Adherence Trajectories and Risk of Cardiotoxicity Among Adults Initiating Anthracycline Treatment

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 2, February 2026.
ABSTRACT Background Poor blood pressure control and low adherence to antihypertensives increase the risk for anthracycline‐induced cardiotoxicity (AIC) in hypertensive cancer patients. Little is known about whether past adherence to antihypertensive medications can reduce the risk of AIC in patients initiating anthracyclines.
Udim Damachi   +3 more
wiley   +1 more source

Reduced Vegetation Uptake During the Extreme 2023 Drought Turns the Amazon Into a Weak Carbon Source

open access: yesAGU Advances, Volume 7, Issue 1, February 2026.
Abstract In 2023, the biogeographic Amazon experienced temperature anomalies of 1.5°C above the 1991–2020 average from September to November. These conditions were driven by high sea surface temperature in the Atlantic and Pacific oceans, together with reduced moisture advection from the Atlantic, causing large vapor pressure and water deficits in the ...
S. Botía   +30 more
wiley   +1 more source

CXCL13 as a Biomarker of Complex Common Variable Immunodeficiency. [PDF]

open access: yesJ Clin Immunol
Karafotias I   +10 more
europepmc   +1 more source

First Derivations of Air‐Sea CO2 Fluxes in the Central Mediterranean and Possible Impact of the 2022–2023 Marine Heatwave

open access: yesJournal of Geophysical Research: Oceans, Volume 131, Issue 2, February 2026.
Abstract Marginal seas significantly impact the global carbon cycle. However, current knowledge on the role of marginal seas is limited, and only a few in situ data sets on air‐sea CO2 exchange are available. This study presents the first direct measurements of CO2 partial pressure (pCO2 ${\text{CO}}_{2}$) and derived air‐sea CO2 ${\text{CO}}_{2}$ flux
Mattia Pecci   +12 more
wiley   +1 more source

A Cell‐Intrinsic Role for RANK in Regulatory T Cells of the Human Thymus [PDF]

open access: yesEur J Immunol
We identified RANK (TNFRSF11a) expression in human thymic FOXP3+ Tregs, revealing a previously unknown role for the RANK‐RANKL axis in human tTreg development. We show that IL‐2 and IL‐15 can drive RANK expression in CD4+ tTregs, which in turn may modulate their maturation and proliferation within the thymic environment. Created in BioRender. Biorender,
Junginger Z   +5 more
europepmc   +2 more sources

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