Results 221 to 230 of about 117,111 (323)
IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak +7 more
wiley +1 more source
CST7<sup>+</sup> macrophages/monocytes in melanoma: single-cell insights into immunotherapy response. [PDF]
Yao K +9 more
europepmc +1 more source
ABSTRACT Background Poor blood pressure control and low adherence to antihypertensives increase the risk for anthracycline‐induced cardiotoxicity (AIC) in hypertensive cancer patients. Little is known about whether past adherence to antihypertensive medications can reduce the risk of AIC in patients initiating anthracyclines.
Udim Damachi +3 more
wiley +1 more source
Chemoradiation of glioblastoma cells alters expression of activation and immune checkpoint molecules on type 1 and 2 dendritic cells and impacts on subsequent T cell proliferation. [PDF]
Schuster C +5 more
europepmc +1 more source
Reduced Vegetation Uptake During the Extreme 2023 Drought Turns the Amazon Into a Weak Carbon Source
Abstract In 2023, the biogeographic Amazon experienced temperature anomalies of 1.5°C above the 1991–2020 average from September to November. These conditions were driven by high sea surface temperature in the Atlantic and Pacific oceans, together with reduced moisture advection from the Atlantic, causing large vapor pressure and water deficits in the ...
S. Botía +30 more
wiley +1 more source
CXCL13 as a Biomarker of Complex Common Variable Immunodeficiency. [PDF]
Karafotias I +10 more
europepmc +1 more source
Abstract Marginal seas significantly impact the global carbon cycle. However, current knowledge on the role of marginal seas is limited, and only a few in situ data sets on air‐sea CO2 exchange are available. This study presents the first direct measurements of CO2 partial pressure (pCO2 ${\text{CO}}_{2}$) and derived air‐sea CO2 ${\text{CO}}_{2}$ flux
Mattia Pecci +12 more
wiley +1 more source
T cells in ITP: Focus on T follicular helper cells and cytotoxic T cells. [PDF]
Audia S, Cooper N.
europepmc +1 more source
A Cell‐Intrinsic Role for RANK in Regulatory T Cells of the Human Thymus [PDF]
We identified RANK (TNFRSF11a) expression in human thymic FOXP3+ Tregs, revealing a previously unknown role for the RANK‐RANKL axis in human tTreg development. We show that IL‐2 and IL‐15 can drive RANK expression in CD4+ tTregs, which in turn may modulate their maturation and proliferation within the thymic environment. Created in BioRender. Biorender,
Junginger Z +5 more
europepmc +2 more sources

