Results 181 to 190 of about 940,297 (279)

Development of a centralized progress management system using lean thinking and efforts to improve operations. [PDF]

open access: yesBMC Health Serv Res
Yahata S   +6 more
europepmc   +1 more source

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

open access: yesAdvanced Science, EarlyView.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han   +9 more
wiley   +1 more source

Cover JICTRA Vol. 14 No. 3, 2021

open access: yesJournal of ICT Research and Applications, 2021
Journal of ICT Research and Applications
doaj  

Viral transduction for T cell engineering in immunotherapy. [PDF]

open access: yesMol Cells
Seo Y, Pak J, Han J, Bae J, Hwang SS.
europepmc   +1 more source

AI‐Optimized Vanadium Oxide Multilayers for More Than 20‐fold Enhancement in Bolometric Performance

open access: yesAdvanced Science, EarlyView.
Machine‐learning‐optimized WxV1‐xOy multilayer thin films with graded doping achieve a high TCR (7.3 % K−1), reduced hysteresis, and low noise under CMOS‐compatible growth conditions. This approach overcomes the long‐standing trade‐off in microbolometers between linear response and performance, offering a universal bolometric parameter greatly enhanced
Jin‐Hyun Choi   +8 more
wiley   +1 more source

Cover JICTRA Vol. 15 No. 1, 2021

open access: yesJournal of ICT Research and Applications, 2021
Journal of ICT Research and Applications
doaj  

Coincident Fluorescence‐Burst Analysis of Actin Cargo Molecules in Secreted Single Diffusing Extracellular Vesicles From Human Induced Pluripotent Stem Cells

open access: yesAdvanced Science, EarlyView.
This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen   +4 more
wiley   +1 more source

Front Matter

open access: yesJournal of ICT Research and Applications, 2021
Journal of ICT Research and Applications
doaj  

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