Results 81 to 90 of about 1,888 (192)

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Microfluidic Hydroporation Platform for Effective Allogeneic CAR‐T Cell Production and Subsequent Functional Cytotoxicity Analysis

open access: yesAdvanced Materials Technologies, EarlyView.
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon   +6 more
wiley   +1 more source

Preservation of Extracellular Vesicle Integrity and Cargo Using Spiral Microfluidic Chip‐Based Separation

open access: yesAdvanced Materials Technologies, EarlyView.
A spiral microfluidic chip is compared with ultrafiltration for the separation of extracellular vesicles (EVs). The method preserves miRNA cargo and membrane integrity more effectively, resulting in intact vesicle morphology and consistent surface biomarker expression.
Huiseop Lee   +5 more
wiley   +1 more source

Quasi‐Single‐Mode Polaritonic Crystal for Hyperbolic Phonon‐Polaritons

open access: yesAdvanced Optical Materials, EarlyView.
Near‐field study of the polaritonic Fourier crystal with α‐MoO3 reveals that the hyperbolic phonon‐polaritons within the Type‐I Reststrahlen band may form a quasi‐single‐mode Bloch wave where only the fundamental mode propagates in the crystal. Our results demonstrate the realization of a quasi‐single‐mode regime for the inherently multimode hyperbolic
Sergey G. Menabde   +7 more
wiley   +1 more source

Visible‐Light Photoprogrammable Transistors Enabled by an All‐Organic Triplet‐Sensitized Diarylethene Channel Layer

open access: yesAdvanced Optical Materials, EarlyView.
All‐organic channel‐layer OFETs are shown to enable visible‐light photoprogramming via triplet‐sensitized diarylethene switching. Preferential localization of the photoswitch and organic sensitizer in intercrystalline amorphous domains preserves polymer crystalline packing while ensuring short‐range Dexter‐type triplet–triplet energy transfer and solid‐
Jieun Kwon   +10 more
wiley   +1 more source

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