Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley +1 more source
Protective Effect of Brain Derived Neurotrophic Factor-Overexpressing Wharton's Jelly-Derived Mesenchymal Stromal Cells in Severe Intraventricular Hemorrhage in Newborn Rats. [PDF]
Jung SY +7 more
europepmc +1 more source
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon +6 more
wiley +1 more source
Protocol for high-content drug screening using tumor organoids on a 384-pillar plate platform. [PDF]
Choi JS, Lee MS, Song MJ, Jeong K.
europepmc +1 more source
A spiral microfluidic chip is compared with ultrafiltration for the separation of extracellular vesicles (EVs). The method preserves miRNA cargo and membrane integrity more effectively, resulting in intact vesicle morphology and consistent surface biomarker expression.
Huiseop Lee +5 more
wiley +1 more source
Evaluation of dental implant with hydroxyapatite coating by laser-induced hydrothermal synthesis: in vitro and in vivo experimental study. [PDF]
Lee JT +10 more
europepmc +1 more source
Quasi‐Single‐Mode Polaritonic Crystal for Hyperbolic Phonon‐Polaritons
Near‐field study of the polaritonic Fourier crystal with α‐MoO3 reveals that the hyperbolic phonon‐polaritons within the Type‐I Reststrahlen band may form a quasi‐single‐mode Bloch wave where only the fundamental mode propagates in the crystal. Our results demonstrate the realization of a quasi‐single‐mode regime for the inherently multimode hyperbolic
Sergey G. Menabde +7 more
wiley +1 more source
CREB2 Functions as a Central Mediator of Oxidative Neuronal Death Triggered by Microglial Glutamate Release Under Neuroinflammatory Conditions. [PDF]
Moon UY, Kim YE, Nguyen HD, Choi HJ.
europepmc +1 more source
All‐organic channel‐layer OFETs are shown to enable visible‐light photoprogramming via triplet‐sensitized diarylethene switching. Preferential localization of the photoswitch and organic sensitizer in intercrystalline amorphous domains preserves polymer crystalline packing while ensuring short‐range Dexter‐type triplet–triplet energy transfer and solid‐
Jieun Kwon +10 more
wiley +1 more source
A convective transport-enhanced multi-organoid device for therapeutic modeling of the liver-pancreas axis in obesity. [PDF]
Kim J, Bae J, Cui B, Cho SW, Yang K.
europepmc +1 more source

