Results 121 to 130 of about 54,706 (331)

A simple model of epileptic seizure propagation: Potassium diffusion versus axo-dendritic spread.

open access: yesPLoS ONE, 2020
The mechanisms of epileptic discharge generation and spread are not yet fully known. A recently proposed simple biophysical model of interictal and ictal discharges, Epileptor-2, reproduces well the main features of neuronal excitation and ionic dynamics
Anton V Chizhov, Aleksei E Sanin
doaj   +1 more source

Electrocardiographic changes in patients with refractory epilepsy

open access: yesJournal of Research in Medical Sciences, 2013
Background: Epilepsy is the second most common type of chronic neurological disease. Its diagnosis carries an excess mortality, which is 2-3 times higher than that of general population.
Mohammad Zare   +4 more
doaj  

Ictal PET in presurgical workup of refractory extratemporal epilepsy

open access: yesAnnals of Indian Academy of Neurology, 2013
Ictal Pet in presurgical workup of refractory epilepsy is seldom performed and limited due to technical difficulties. In carefully selected patient subset with frequent extratemporal seizures, ictal PET depicts ′seizure onset zone′ with high spatial ...
Javeria Nooraine   +2 more
doaj   +1 more source

Seizure onset zone localization from ictal high-density EEG in five patients [PDF]

open access: yes, 2015
Rationale Because epilepsy is a network disease, localization of the exact seizure onset zone (SOZ) is difficult because the epileptic activity can spread to other regions within milliseconds.
Birot, Gwénaël   +8 more
core   +1 more source

A guide to neuromodulation in drug‐resistant epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh   +10 more
wiley   +1 more source

Cardiorespiratory cross‐frequency coupling biomarker for sudden unexpected death in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Sudden unexpected death in epilepsy (SUDEP) often follows generalized tonic–clonic seizures during sleep, likely resulting from impaired brainstem cardiorespiratory function. We used ictal electrocardiogram (ECG)‐based cross‐frequency phase–amplitude coupling (PAC) to detect cardiorespiratory disruptions, comparing SUDEP to non‐SUDEP
Adam C. Gravitis   +7 more
wiley   +1 more source

Ictal laughter and crying: Should they be classified as automatisms?

open access: yesEpilepsy and Behavior Case Reports, 2017
Gelastic seizures (GS) describe ictal laughter and are associated with hypothalamic lesions, as well as other cortical areas. Dacrystic seizures (DS), characterized by ictal crying, also have been reported in hypothalamic lesions and focal epilepsy.
Anna-Marieta Moise   +4 more
doaj   +1 more source

Quantifying the impact of a computer‐aided diagnostic score on the clinical diagnosis of functional seizures

open access: yesEpilepsia, EarlyView.
Abstract Objective The diagnosis of functional/dissociative seizures (FDS) without ictal video‐electroencephalography is challenging. The Functional/Dissociative Seizures Likelihood Score (FSLS) is a machine learning‐based diagnostic score that aims to help clinicians identify FDS.
Wesley T. Kerr   +38 more
wiley   +1 more source

Lennox–Gastaut syndrome in a patient with biallelic TELO2 variants

open access: yes
Epileptic Disorders, EarlyView.
Melissa Odabassian, Kenneth A. Myers
wiley   +1 more source

Timing is everything: Expert opinion on researching epilepsy rhythms by the ILAE Task Force on Chronobiology

open access: yesEpilepsia, EarlyView.
Abstract Recurrent seizures, the hallmark of epilepsy, are influenced by rhythms operating over multiple timescales. Chronobiology is the study of biological timing that aims to explain temporal patterns of events like seizures. Fueled by recent advances in genetics, computational modeling, and device engineering, the chronobiology of epilepsy is now a
Maxime O. Baud   +4 more
wiley   +1 more source

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