Results 151 to 160 of about 54,706 (331)

Exploring pathways leading to drug‐resistant epilepsy for patients with cryptogenic new onset refractory status epilepticus

Epilepsia, EarlyView.
Abstract Objective Cryptogenic new onset refractory status epilepticus (cNORSE) carries high risks of long‐term disability and post‐NORSE epilepsy, but mechanisms remain unclear. We aimed to assess the predictive value of inflammatory and brain injury biomarkers and determine whether immune disturbances persist in the chronic phase. Methods We enrolled
Aurélie Hanin, Clémence Marois, Martin Guillemaud, Mario Chavez, Léa Cosme, Zineb Hayatou, Aurore Besnard, Gwen Goudard, Véronique Masson, Louis Cousyn, Margaux Cheval, Jérôme A. Denis, Rana Alkouri, Foudil Lamari, Francesca Bisulli, Krista Eschbach, Raquel Farias‐Moeller, Nicolas Gaspard, Elizabeth E. Gerard, Giada Giovannini, Teneille Gofton, Margaret T. Gopaul, Marissa Kellogg, Stefano Meletti, Lorenzo Muccioli, Elena Pasini, Olga Taraschenko, Nathan Torcida, Mark S. Wainwright, Ji Yeoun Yoo, Nora Wong, Dominique Bonnefont‐Rousselot, Sophie Demeret, Lawrence J. Hirsch, Vincent Navarro   +34 more
wiley   +1 more source

Persons with epilepsy and their caregivers understand the definition of ictal impairment of consciousness

Epilepsia, EarlyView.
Abstract The term consciousness has been reintroduced in the updated seizure classification. Concerns have been raised that "ictal impaired consciousness" may be misunderstood by persons with epilepsy (PWEs) and their caregivers, particularly that English‐speaking individuals might equate it with complete loss of consciousness.
Kaley J. Marcinski Nascimento, Fábio A. Nascimento, Torie Robinson, Birgit Frauscher, Eugen Trinka, Sándor Beniczky   +5 more
wiley   +1 more source

Severe peri-ictal respiratory dysfunction is common in Dravet syndrome

Journal of Clinical Investigation, 2018
Yujaung Kim, Eduardo Bravo, Caitlin K. Thirnbeck, Lori A Smith-Mellecker, S. H. Kim, B. Gehlbach, L. Laux, Xiuqiong Zhou, D. Nordli, G. Richerson   +9 more
semanticscholar   +1 more source

Graded extent of hippocampal resection is related to neuropsychological outcomes in temporal lobe epilepsy surgery

Epilepsia, EarlyView.
Abstract Objective Surgical resection for epilepsy seeks to maximize seizure freedom while minimizing new neurocognitive impairments. Tailored resections guided by anatomoelectroclinical (AEC) hypotheses offer the possibility of sparing parts of the hippocampus.
Eliza M. Reedy, Emma Robinson, Thandar Aung, Catherine Liégeois‐Chauvel, Danielle R. Carns, Natalie Sherry, Luke C. Henry, Bradford Z. Mahon, Arka N. Mallela, Jorge A. Gonzalez‐Martinez   +9 more
wiley   +1 more source

Intracranial electroencephalographic connectivity analysis to localize epileptogenic networks: Systematic review and meta‐analysis from ILAE Epilepsy Surgery Networks Task Force

Epilepsia, EarlyView.
Abstract Intracranial electroencephalographic (iEEG) connectivity analysis is a promising method to localize epileptic networks and guide surgical planning in focal drug‐resistant epilepsy. Despite numerous studies exploring its utility, the added value of iEEG connectivity over standard clinical presurgical evaluation remains unclear.
Nishant Sinha, Daniel J. Zhou, Victoria L. Morgan, Dario J. Englot, Leonardo Bonilha, Milan Brázdil, Xiaosong He, Riki Masumoto, Quy Cao, Terence J. O'Brien, Chengyuan Wu, Erik Kaestner, Carrie McDonald, Ezequiel Gleichgerrcht, Aileen McGonigal, Kathryn A. Davis   +15 more
wiley   +1 more source

Ictal Vomiting

Pediatric Neurology Briefs, 1988
Paroxysmal vomiting in 9 patients, 3 children (7, 8, and 11 years of age) and 6 young adults, is reported from the Section of Epilepsy and Clinical Neurophysiology, Cleveland Clinic, Cleveland, OH.
openaire   +3 more sources

Defining the end point of status epilepticus: A scoping review and framework for standardization

Epilepsia, EarlyView.
Abstract Status epilepticus (SE) is a life‐threatening neurological emergency with consensus‐driven definitions for onset but no standardized criteria for its end point. This gap creates uncertainty in research and clinical practice. We conducted a scoping review to evaluate how end points have been defined in SE research and to identify key areas of ...
Fawad A. Khan, Margaret T. Gopaul, Samuel L. Carter, Anil Chimakurthy, Summer Skelton, Lawrence J. Hirsch, Eugen Trinka   +6 more
wiley   +1 more source

Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin, Alicia Janvier, Tristan Moujellil‐Legagneur, Marine Blaquière, Alexis Chaussy, Romane Privé, Fabrice Duprat, Massimo Mantegazza, Etienne Audinat, Nicola Marchi, Noémie Cresto   +10 more
wiley   +1 more source

Determinants of successful ictal SPECT injection in phase 1 epilepsy presurgical evaluation: Findings from the pediatric epilepsy research consortium surgery database project

Epilepsia Open
Objectives The main goal of presurgical evaluation in drug‐resistant focal epilepsy is to identify a seizure onset zone (SOZ). Of the noninvasive, yet resource‐intensive tests available, ictal single‐photon emission computed tomography (SPECT) aids SOZ ...
Charuta Joshi, Rani Singh, Gang Liu, Cemal Karakas, Michael Ciliberto, Krista Eschbach, M. Scott Perry, Daniel Shrey, Tricia Morphew, Adam P. Ostendorf, Shilpa B. Reddy, Michael J. McCormack, Samir Karia, Shrishti Nangia, Lily Wong‐Kisiel, the PERC Surgery Workgroup   +15 more
doaj   +1 more source