Results 251 to 260 of about 55,052 (379)

Synaptic ultrastructural alterations in human focal cortical dysplasia: Insights from volume electron microscopy

Epilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a developmental malformation of the cerebral cortex and a leading cause of drug‐resistant epilepsy in children and young adults. Disruption of the excitation–inhibition (E–I) balance is a hallmark of neuronal hyperexcitability in FCD, yet the underlying synaptic ultrastructural changes remain poorly ...
Gyu Hyun Kim, Na‐Young Seo, Seung‐Ki Kim, Jae‐Kyung Won, Yang Hoon Huh, Ji Yeoun Lee, Kea Joo Lee   +6 more
wiley   +1 more source

The future is in the background: background EEG patterns, not acute seizures, predict epilepsy and neurodevelopmental outcomes in neonatal HIE. [PDF]

Front Pediatr
Woodward KE, de Jesus P, Amador K, Mouches P, Braun M, Mohammad K, Forkert ND, Esser MJ.   +7 more
europepmc   +1 more source

Ictal Depth EEG and MRI Structural Evidence for Two Different Epileptogenic Networks in Mesial Temporal Lobe Epilepsy

, 2015
Negar Memarian, Sarah K. Madsen, Paul M. Macey, Itzhak Fried, Jerome Engel, Paul M. Thompson, Richard J. Staba   +6 more
openalex   +2 more sources

Digital Response Test in Epilepsy assesses interictal epileptiform discharge effects in real time

Epilepsia, EarlyView.
Abstract Objective Interictal epileptiform discharges (IEDs) in people with epilepsy (PWE) can impair cognitive functions and increase reaction time (RT) and the likelihood of missed reactions. These effects are not routinely assessed, because reliable methods for detecting IEDs of variable appearance in real time and suitable tests to measure IED ...
Andreas von Allmen, Diyuan Lu, Caroline Jagella, Yasmina Abukhadra, Rune Markhus, Jochen Triesch, Margaret Gopaul, Lawrence J. Hirsch, Felix Rosenow, Hal Blumenfeld, Heinz Krestel   +10 more
wiley   +1 more source

Cluster headache suicidality: a systematic review with a meta-analysis. [PDF]

J Headache Pain
Van Obberghen EK, Fabre R, Lanteri-Minet M.   +2 more
europepmc   +1 more source

The effective connectivity of the seizure onset zone and ictal perfusion changes in amygdala kindled rhesus monkeys

, 2016
Evy Cleeren, Elsie Premereur, Cindy Casteels, Karolien Goffin, Peter Janssen, Wim Van Paesschen   +5 more
openalex   +1 more source

Diagnostic performance of 18F-FDG PET and ictal 99mTc-HMPAO SPET in pediatric temporal lobe epilepsy: Quantitative analysis by statistical parametric mapping, statistical probabilistic anatomical map, and subtraction ictal SPET [PDF]

, 2005
Joongku Lee, Won Jun Kang, Dong Soo Lee, Jae Sung Lee, Hee Hwang, Ki Joong Kim, Yong-Seung Hwang, June‐Key Chung, Myung Chul Lee   +8 more
openalex   +1 more source

Potassium–chloride cotransporter 2 activity dampens induced ictal‐like activity in neocortical slices containing the seizure propagation zone of temporal lobe epilepsy patients

Epilepsia, EarlyView.
The K⁺/Cl− cotransporter (KCC2) limits induced ictal‐like events and their spread in the supragranular layer of human neocortical slices from the seizure‐propagation zone of temporal lobe epilepsy patients. Cl⁻ extrusion is present in supragranular pyramidal neurons but limited under high somatic Cl⁻ load.
Alice Falck, Janna Lehnhoff, Mahraz Behbood, Egor Byvaltcev, Annette Aigner, Helena Radbruch, Pawel Fidzinski, Jan‐Hendrik Schleimer, Gabriel M. S. Janach, Noah Döhne, Julia Onken, Thilo Kalbhenn, Thomas Sauvigny, Rudolf A. Deisz, Susanne Schreiber, Martin Holtkamp, Ulf Strauss   +16 more
wiley   +1 more source

Seizure classification using a multimodal seizure monitoring system (Nelli) in Dravet and Lennox–Gastaut syndromes: A non‐randomized, single‐center feasibility study

Epilepsia, EarlyView.
Abstract Objective This study aimed to assess the performance of the Nelli seizure monitoring system in detecting and classifying seizures during sleep or while at rest in bed in patients with Lennox–Gastaut syndrome (LGS) and Dravet syndrome (DS). Methods We conducted a non‐interventional, single‐center feasibility study from August 2023 to March 2024,
Line Kønig Wilms, Morten I. Lossius, Kaapo Annala, Jonas Abdel‐Khalik, Lena Fanter, Kaisa Elomaa, Jukka Peltola   +6 more
wiley   +1 more source

Typical ictal pattern on MR perfusion scan for patients on the ictal-interictal continuum. [PDF]

Epileptic Disord
Huynh Mabry M, Dadhich H, Yetkin Z, Sheikh I.   +3 more
europepmc   +1 more source