Results 11 to 20 of about 895,090 (346)

Early Active Mobilization during Mechanical Ventilation in the ICU.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND Intensive care unit (ICU)-acquired weakness often develops in patients who are undergoing invasive mechanical ventilation. Early active mobilization may mitigate ICU-acquired weakness, increase survival, and reduce disability.
C. Hodgson   +19 more
semanticscholar   +1 more source

Restriction of Intravenous Fluid in ICU Patients with Septic Shock.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND Intravenous fluids are recommended for the treatment of patients who are in septic shock, but higher fluid volumes have been associated with harm in patients who are in the intensive care unit (ICU). METHODS In this international, randomized
T. Meyhoff   +67 more
semanticscholar   +1 more source

Haloperidol for the Treatment of Delirium in ICU Patients

open access: yesNew England Journal of Medicine, 2022
METHODS In this multicenter, blinded, placebo-controlled trial, we randomly assigned adult patients with delirium who had been admitted to the ICU for an acute condition to receive intravenous haloperidol (2.5 mg 3 times daily plus 2.5 mg as needed up to
N. Andersen-Ranberg   +46 more
semanticscholar   +1 more source

ICU-acquired weakness

open access: yesIntensive Care Medicine, 2020
Critically ill patients often acquire neuropathy and/or myopathy labeled ICU-acquired weakness. The current insights into incidence, pathophysiology, diagnostic tools, risk factors, short- and long-term consequences and management of ICU-acquired ...
I. Vanhorebeek   +2 more
semanticscholar   +1 more source

COVID-19 increased the risk of ICU-acquired bloodstream infections: a case–cohort study from the multicentric OUTCOMEREA network

open access: yesIntensive Care Medicine, 2021
The primary objective of this study was to investigate the risk of ICU bloodstream infection (BSI) in critically ill COVID-19 patients compared to non-COVID-19 patients.
N. Buetti   +8 more
semanticscholar   +1 more source

Conservative Oxygen Therapy during Mechanical Ventilation in the ICU.

open access: yesNew England Journal of Medicine, 2020
BACKGROUND Patients who are undergoing mechanical ventilation in the intensive care unit (ICU) often receive a high fraction of inspired oxygen (Fio2) and have a high arterial oxygen tension.
D. Mackle   +14 more
semanticscholar   +1 more source

Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU

open access: yesCritical Care Medicine, 2018
Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design: Thirty-two international experts, four methodologists, and four critical illness survivors met
J. Devlin   +40 more
semanticscholar   +1 more source

COVID-19: ICU delirium management during SARS-CoV-2 pandemic

open access: yesCritical Care, 2020
The novel coronavirus, SARS-CoV-2-causing Coronavirus Disease 19 (COVID-19), emerged as a public health threat in December 2019 and was declared a pandemic by the World Health Organization in March 2020.
K. Kotfis   +6 more
semanticscholar   +1 more source

Timing of antibiotic therapy in the ICU

open access: yesCritical Care, 2021
Severe or life threatening infections are common among patients in the intensive care unit (ICU). Most infections in the ICU are bacterial or fungal in origin and require antimicrobial therapy for clinical resolution.
M. Kollef   +6 more
semanticscholar   +1 more source

The effect of adding comorbidities to current centers for disease control and prevention central-line–associated bloodstream infection risk-adjustment methodology [PDF]

open access: yes, 2017
BACKGROUNDRisk adjustment is needed to fairly compare central-line–associated bloodstream infection (CLABSI) rates between hospitals. Until 2017, the Centers for Disease Control and Prevention (CDC) methodology adjusted CLABSI rates only by type of ...
Anderson, Deverick J   +11 more
core   +2 more sources

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