Results 321 to 330 of about 895,090 (346)

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

Potentially MOdifiable factors To ImproVe outcomes of mechanically Ventilated patients in a low-income country Intensive Care Units (MOTIVATE-ICU): rationale and protocol for a registry-embedded prospective observational study. [PDF]

Crit Care Sci
Sendagire C, Pisani L, Nuwagira A, Hewitt-Smith A, Nakibuuka J, Kiwalya H, Ayupo NC, Ogwal D, Kakaire D, Atumanya P, Khainza B, Nakayiza H, Nakandi H, Tomanya K, Alupo M, Ssemogerere L, Okello E, Lubikire A, Kintu A, Nyeko I, Kamau A, Kodippily C, Kwizera A, Beane A, Haniffa R, Salluh JIF.   +25 more
europepmc   +1 more source

Acute kidney injury and iron metabolism: A narrative review focusing on pathophysiology and therapy

Smart Molecules, EarlyView.
Schematic illustration of acute kidney injury and iron metabolism (By Figdraw). Image for iron metabolism, including uptake, storage, utilization, export: Reproduced with permission. Abstract Acute kidney injury (AKI) represents a substantial challenge to public health and is characterized by elevated occurrence and fatality rates.
Xinyu Tan, Man Li, Jing Chen, Gang Liu, Zhixiang Lu   +4 more
wiley   +1 more source

The association between blood urea nitrogen to albumin ratio and 28-day ICU mortality in sepsis patients: a retrospective cohort study. [PDF]

Eur J Med Res
Wu M, Sun H, Lv H, Zhu A.
europepmc   +1 more source

Risk Factors of Post-Traumatic Stress Disorder Symptom Trajectories for ICU Bereaved Family Members

Fur‐Hsing Wen, Li‐Pang Chuang, Tsung‐Hui Hu, Chung-Chi Huang, Wen‐Chi Chou, Siew Tzuh Tang   +5 more
openalex   +2 more sources

Impact of fluid creep on volume and chloride load in critically ill adults: a prospective study on its prognostic significance and association with MAKE30. [PDF]

Ren Fail
Zhou D, Cao F, Zhang L, Qiu G, Chen Y, Li Y, Peng Z.   +6 more
europepmc   +1 more source

Implementation of a new technique to improve subglottic secretion mobilization in tracheotomized ICU patients: The "volcano method"

Niraula, Birat Bikram, Brendebach, Luca, Lenherr, Renato, Perret, Claudio, Probst, Ilona, Mostberger, Sven, Stierli, Sarah, Mueller, Gabi   +7 more
openalex   +1 more source

Work-related stress in intensive care unit night shift nurses: A cross-sectional analysis of prevalence and determinants. [PDF]

PLoS One
Reshia FAA, Abo Seada AI, Salameh B, Abdallah J, Alruwaili EMR, Salama ESS, Alrumieh WG, Elnosary AMA.   +7 more
europepmc   +1 more source

Prolonged prone positioning in ARDS: No mortality benefit, no increased risk-But what about the reduced ICU staff workload? [PDF]

Crit Care
Domizi R, Damiani E, Carsetti A, Adrario E, Donati A.   +4 more
europepmc   +1 more source