Results 121 to 130 of about 18,587 (226)

DRL‐Fit: Determining Rate Constants In Multistep Reactions From ESI‐MS Data

open access: yesChemistry–Methods, Volume 5, Issue 12, November 2025.
DRL‐Fit is a Python program that can fit a kinetic model to delayed reactant labeling data from ESI‐MS experiments, allowing rate constants to be determined in a multistep reaction. Consequently, the concentrations of all the involved molecules can be determined. This is applied to the nitro‐Mannich reaction to showcase the capabilities and limitations
Matthijs A. Hellinghuizen   +2 more
wiley   +1 more source

Human Heart Disease Prediction System Using Data Mining Techniques

open access: yesSir Syed University Research Journal of Engineering and Technology, 2019
— Prediction of heart disease is a big concern now a days because everyone is busy and due to heavy load of work people do not give attention to their health. To diagnose a disease is a big challenge.
Sidra Javed   +3 more
doaj  

Intron Retention Generates a Novel Id3 Isoform That Inhibits Vascular Lesion Formation [PDF]

open access: hybrid, 2004
Scott Forrest   +4 more
openalex   +1 more source

Prenatal genetic counselors' attitudes, beliefs, and practices with discussing postnatal Duchenne muscular dystrophy treatment options

open access: yesJournal of Genetic Counseling, Volume 34, Issue 6, December 2025.
Abstract Duchenne muscular dystrophy (DMD) is an X‐linked genetic condition characterized by progressive muscle degeneration. Recently, several genotype‐specific treatment options for DMD have become available. Prenatal genetic counselors may encounter at‐risk patients for DMD, through a variety of indications.
Shawna L. Jurlina   +3 more
wiley   +1 more source

Employment management system for universities based on improved decision tree

open access: yesJournal of Intelligent Systems
With the popularization of higher education, the number of students in colleges and universities is increasing, and how to timely cope with the various problems faced by students in employment has become a major problem faced by teachers in colleges and ...
Li Jing, Ma Yongsheng
doaj   +1 more source

Improved Regression Tree Models Using Generalization Error‐Based Splitting Criteria

open access: yesNaval Research Logistics (NRL), Volume 72, Issue 8, Page 1097-1116, December 2025.
ABSTRACT Despite the widespread application of machine learning (ML) approaches such as the regression tree (RT) in the field of data‐driven optimization, overfitting may impair the effectiveness of ML models and thus hinder the deployment of ML for decision‐making.
Ying Yang, Shuaian Wang, Gilbert Laporte
wiley   +1 more source

Single‐Cell Atlas of Aging Human Skin Reveals FOSB‐Related Transcriptional Programs and Druggable Targets

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 12, December 2025.
ABSTRACT Background While human skin aging involves complex transcriptional alterations, the cell‐type‐specific regulatory mechanisms and therapeutic targets remain incompletely defined. The study aims to investigate aging‐associated transcriptional programs and drug‐responsive signatures at single‐cell resolution.
Youcheng Zhang   +4 more
wiley   +1 more source

Nanodroplet‐Array‐Plattform zur integrierten Synthese und Screening von MEK Inhibitoren: Ein miniaturisierter Ansatz für die frühe Pharmaforschung

open access: yesAngewandte Chemie, Volume 137, Issue 48, November 24, 2025.
Wir präsentieren eine Nanodroplet‐Array‐Plattform, die die Integration von Festphasensynthese, MALDI‐MS‐Analyse und zellbasiertem Screening von 325 potenziellen MEK‐Inhibitoren (Mitogen‐aktivierte‐Proteinkinase‐Kinase) in Nanoliter‐Volumina ermöglicht.
Maximilian Seifermann   +10 more
wiley   +1 more source

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