Results 131 to 140 of about 18,587 (226)

Nanodroplet Array Platform for Integrated Synthesis and Screening of MEK Inhibitors: a Miniaturized Approach to Early Drug Discovery

Angewandte Chemie International Edition, Volume 64, Issue 48, November 24, 2025.
We present a nanodroplet array platform that integrates solid‐phase synthesis, MALDI‐MS analysis, and cell‐based screening. Using nanoliter droplets, we synthesized and tested 325 potential MEK inhibitors and identified 46 active compounds. This miniaturized approach combines chemistry and biology on a single chip, reducing time, cost, and material use
Maximilian Seifermann, Julius Höpfner, Liana Bauer, Divya Varadharajan, Stefan Schmidt, Björn Fröhlich, Benjamin Wellenhofer, Charlotte Luchena, Carsten Hopf, Anna A. Popova, Pavel A. Levkin   +10 more
wiley   +1 more source

Evaluation of Public Hospitals' Performance with Decision Tree Algorithms

Verimlilik Dergisi
Purpose: The study aims to evaluate a range of financial performance indicators calculated through structural, operational, and HVI measures for public hospitals in the Turkish healthcare sector using various decision tree algorithms.
Keziban Avcı
doaj   +1 more source

Aberrant production of IL-13 by T cells promotes exocrinopathy in Id3 knockout mice

, 2014
Ian Belle, Josh Mahlios, Andrew N. J. McKenzie, Yuan Zhuang   +3 more
openalex   +1 more source

ID1 and ID3 represent conserved negative regulators of human embryonic and induced pluripotent stem cell hematopoiesis [PDF]

, 2011
Seok‐Ho Hong, Jong‐Hee Lee, Jung Bok Lee, Junfeng Ji, Mickie Bhatia   +4 more
openalex   +1 more source

Vascular Injury Induces Posttranscriptional Regulation of the Id3 Gene [PDF]

, 2001
Martin E. Matsumura, Feng Li, Lionel Berthoux, Beiyang Wei, David R. Lobe, Cathy Jeon, Coleen A. McNamara   +6 more
openalex   +1 more source

B-1B Cells are a Novel Atheroprotective B Cell Subset and are Negatively Regulated by ID3

, 2015
Samuel Morris-Rosenfeld
openalex   +1 more source

ID3-IR1050-NIR_II-preinj.tif

, 2017
Zbigniew Starosolski
openalex   +1 more source

Immunoregulation mechanism of Treg cells in anti-GBM glomerulonephritis model of mice

Linchuang shenzangbing zazhi, 2017
Objective To explore the immunoregulation mechanism of Treg cells in anti-GBM glomerulonephritis model of mice,and provide theoretical basis for early intervention of immune response and alleviating pathologic damage.
ZHOU Huan, ZHANG Xin, HE Yong, PENG Qing-ping, WANG Xiao-hui   +4 more
doaj  

Soft Discretization in a Classification Model for Modeling Adaptive Route Choice with a Fuzzy ID3 Algorithm

, 2008
Kyounga Park, Michael G.H. Bell, Ioannis Kaparias, Heidrun Belzner   +3 more
openalex   +2 more sources

Qixian Tongluo Formula promotes the directional differentiation of neural stem cells into neurons via fibrinogen-mediated BMPRI/ID3 signal axis after ischemic stroke. [PDF]

Orphanet J Rare Dis
Zhou S, Li B, Mao G, Zeng W, Chen Y, Huang J, Tan L, Wu D, Liu F.   +8 more
europepmc   +1 more source