Results 171 to 180 of about 49,333 (314)
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman +2 more
wiley +1 more source
Hyperlipemia and Oxidation of LDL Induce Vascular Smooth Muscle Cell Growth: An Effect Mediated by the HLH Factor Id3 [PDF]
Angela M. Taylor +7 more
openalex +1 more source
KRAS‐G12C: The neglected biomarker to detect patients with MUTYH‐associated polyposis
What's new? MUTYH‐associated polyposis is an underdiagnosed recessive syndrome that predisposes individual to colorectal cancer and frequently displays KRAS‐G12C mutations. By analyzing a large cohort of colorectal cancer patients routinely tested for KRAS, the authors assessed whether KRAS‐G12C detection could serve as a pre‐screening tool for the ...
Ana Beatriz Deleame Medeiros +9 more
wiley +1 more source
BAF_S05_Plate Reader SpectraMax iD3 v1
Standard operation of the SpectraMax iD3 plate reader.
openaire +1 more source
Smaller feature size impairs densification in digital light processing 3D printed ceramic samples
Abstract In this study, we investigate how geometric miniaturization affects the sintering densification behavior of alumina cylinders with various wall thicknesses (down to ∼500 µm in green body) fabricated via digital light processing (DLP). As the wall thickness decreased, the density of the sintered samples consistently declined.
Jinwoo Lee +7 more
wiley +1 more source
Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
wiley +1 more source
Lung Microphysiological System Validates Novel Cell Therapy for Acute Respiratory Distress Syndrome
This study aims to evaluate the efficacy of primed mesenchymal stem cells (pMSCs) as an alternative treatment for Acute Respiratory Distress Syndrome (ARDS), based on a novel lung microphysiological system (MPS) to test the efficacy of pMSCs over the standard treatment, Dexamethasone.
Bokyong Kim +11 more
wiley +1 more source
Immunoregulation mechanism of Treg cells in anti-GBM glomerulonephritis model of mice
Objective To explore the immunoregulation mechanism of Treg cells in anti-GBM glomerulonephritis model of mice,and provide theoretical basis for early intervention of immune response and alleviating pathologic damage.
ZHOU Huan +4 more
doaj

