Results 51 to 60 of about 18,587 (226)

Depletion of ID3 enhances mesenchymal stem cells therapy by targeting BMP4 in Sjögren’s syndrome

Cell Death and Disease, 2020
Mesenchymal stem cell (MSCs) transplantation has been used to treat Sjögren’s syndrome (SS) based on the immunoregulatory properties of MSCs. However, the effectiveness need improving and its underlying intrinsic mechanisms remain largely unknown.
Lei Hu, Junji Xu, Tingting Wu, Z. Fan, Lingyun Sun, Yi Liu, Yan Li, Chunmei Zhang, Jingsong Wang, Yaozhong Ding, Songlin Wang   +10 more
semanticscholar   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

A mechanism misregulating p27 in tumors discovered in a functional genomic screen. [PDF]

PLoS Genetics, 2007
The cyclin-dependent kinase inhibitor p27(KIP1) is a tumor suppressor gene in mice, and loss of p27 protein is a negative prognostic indicator in human cancers. Unlike other tumor suppressors, the p27 gene is rarely mutated in tumors.
Carrie M Garrett-Engele, Michael A Tasch, Harry C Hwang, Matthew L Fero, Roger M Perlmutter, Bruce E Clurman, James M Roberts   +6 more
doaj   +1 more source

Iterative Dichotomizer 3 (ID3) Decision Tree: A Machine Learning Algorithm for Data Classification and Predictive Analysis

International Journal of Advanced Engineering Research and Science, 2020
— Decision trees are very important machine learning algorithms used for the classification and predictive analytic purposes in computer science and related disciplines. ID3 decision tree algorithm was designed by Quinlan in 1986.
E. E. Ogheneovo, Promise A. Nlerum
semanticscholar   +1 more source

Lung Microphysiological System Validates Novel Cell Therapy for Acute Respiratory Distress Syndrome

Advanced Biology, EarlyView.
This study aims to evaluate the efficacy of primed mesenchymal stem cells (pMSCs) as an alternative treatment for Acute Respiratory Distress Syndrome (ARDS), based on a novel lung microphysiological system (MPS) to test the efficacy of pMSCs over the standard treatment, Dexamethasone.
Bokyong Kim, So‐Hui Kim, Jieun Kim, Eun‐Young Eo, Hyung‐Jun Kim, Jae Ho Lee, Choon‐Taek Lee, Taeho Kong, Su Kyoung Seo, Seunghee Lee, Jeongbin Park, Young‐Jae Cho   +11 more
wiley   +1 more source

A functionally significant polymorphism in ID3 is associated with human coronary pathology.

PLoS ONE, 2014
AimsWe previously identified association between the ID3 SNP rs11574 and carotid intima-media thickness in the Diabetes Heart Study, a predominantly White diabetic population.
Ani Manichaikul, Stephen S Rich, Heather Perry, Joseph Yeboah, Michelle Law, Molly Davis, Matthew Parker, Michael Ragosta, Jessica J Connelly, Coleen A McNamara, Angela M Taylor   +10 more
doaj   +1 more source

Classification of Images Using Decision Tree [PDF]

Engineering and Technology Journal, 2013
In this paper, the proposed system is based on texture features classification for multi object images by using decision tree (ID3) algorithm. The proposed system uses image segment tile base to reduce the block effect and uses (low low) Wavelet Haar to ...
Emad K. Jabbar, Mayada jabbar kelain
doaj   +1 more source

ANALISA PREDIKSI EFEK KERUSAKAN GEMPA DARI MAGNITUDO (SKALA RICHTER) DENGAN METODE ALGORITMA ID3 MENGGUNAKAN APLIKASI DATA MINING ORANGE

, 2020
Earthquakes are relatively common natural disasters in Indonesia, mainly due to the interaction of tectonic plates. In this study the seismic energy recorded on the seismograph was measured on the Richter Scale (SR). The dataset collected during Semester
Lukman Irawan, Liyando Hermawan Hasibuan, Fauzi Fauzi   +2 more
semanticscholar   +1 more source

Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells

Advanced Functional Materials, EarlyView.
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri, Xinan Huang, Emanuel Lörtscher, Cora‐Ann Schoenenberger, Cornelia G. Palivan   +4 more
wiley   +1 more source

Using High‐Throughput Screening to Identify Crosslinking Peptides That Control Cell‐Mediated Matrix Degradation

Advanced Healthcare Materials, EarlyView.
Protease‐degradable hydrogels mimic dynamic cell‐matrix interactions, but controlling hydrogel degradation is a challenge. We screen libraries of peptides to identify sequences that are primarily degraded by membrane‐localized proteases. Crosslinking hydrogels with these peptides enables cell to spread and migrate while reducing matrix degradation ...
Yingjie Wu, Samuel J. Rozans, Abolfazl Salehi Moghaddam, E. Thomas Pashuck   +3 more
wiley   +1 more source