Results 71 to 80 of about 18,587 (226)

CD5L Promotes M2 Macrophage Polarization through Autophagy-Mediated Upregulation of ID3

open access: yesFrontiers in Immunology, 2018
CD5L (CD5 molecule-like) is a secreted glycoprotein that controls key mechanisms in inflammatory responses, with involvement in processes such as infection, atherosclerosis, and cancer.
L. Sanjurjo   +7 more
semanticscholar   +1 more source

TREM2‐Mediated Cholesterol Efflux in Macrophages Inhibits Anti‐Tumor Immunity via Limitation of CD4+ T and NK Cells

open access: yesAdvanced Science, EarlyView.
Impaired anti‐tumor immunity is mediated by TREM2 + macrophages in non‐small cell lung cancer. TREM2 + macrophages prevent anti‐tumor immunity depending on the limitation of CD4 + T and NK cells. TREM2 promotes cholesterol efflux via ABCA1 to limit the production of CX3CL1 in macrophages.
Yunhan Wang   +9 more
wiley   +1 more source

Selección aleatoria de criterios de división

open access: yesSerie Científica de la Universidad de las Ciencias Informáticas, 2019
La clasificación es una de las tareas más utilizadas de la minería de datos. Dentro de ella existen numerosos algoritmos como las redes neuronales, k vecinos más cercanos, clasificadores bayesianos entre otros.
Alejandro Giubel Hernández Arbelo   +1 more
doaj  

ANALISA PREDIKSI MAHASISWA DROP OUT MENGGUNAKAN METODE DECISION TREE DENGAN ALGORITMA ID3 dan C4.5

open access: yes, 2020
The case of drop out at the Weleri STEKOM is often done by the campus. Drop out is a problem that is often done by Weleri STEKOM students because of a GPA of less than 2, Number of organizations followed, Tuition not paid for students and student who ...
L. Haidar, Eko Sediyono, Ade Iriani
semanticscholar   +1 more source

Nanofluid‐Enhanced Laser Lithotripsy Using Conducting Polymer Nanoparticles

open access: yesAdvanced Science, EarlyView.
Incorporating polymeric nanoparticles, PEDOT:PSS, with a high near‐infrared absorption coefficient into the fluid significantly enhances the dusting efficiency of Ho:YAG laser lithotripsy for kidney stone treatment. This approach, which leverages the control of light‐matter interactions, integrates seamlessly with the current laser lithotripsy workflow.
Qingsong Fan   +10 more
wiley   +1 more source

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

open access: yesAdvanced Science, EarlyView.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou   +18 more
wiley   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

open access: yesAdvanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi   +18 more
wiley   +1 more source

Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early‐Onset Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning   +18 more
wiley   +1 more source

ID2 and ID3 are indispensable for Th1 cell differentiation during influenza virus infection in mice

open access: yesEuropean Journal of Immunology, 2019
Antigen‐specific Th1 cells could be a passage to the infection sites during infection to execute effector functions, such as help CD8+ T cells to localize in these sites by secretion of anti‐viral cytokines‐IFN‐γ or direct cytotoxicity of antigen‐bearing
Xiaojuan Han   +6 more
semanticscholar   +1 more source

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