Results 21 to 30 of about 5,124 (246)

Idarucizumab (Praxbind®) for dabigatran reversal in patients undergoing heart transplantation: a cohort of ten patients

open access: goldFuture Science OA, 2021
Background: Novel oral anticoagulants are used in atrial fibrillation. Idarucizumab has been approved for reversal of dabigatran in situations of life-threatening hemorrhage or emergency surgery.
Eran Kalmanovich   +12 more
doaj   +2 more sources

Use of idarucizumab for emergency surgery in patients taking dabigatran

open access: yesАтеротромбоз, 2022
This article presents modern possibilities for the provision of emergency surgical care to patients with atrial fibrillation, who administered dabigatran etexilate.
O. M. Nesterova   +5 more
doaj   +2 more sources

Successful intravenous thrombolysis in acute ischemic stroke after reversal of dabigatran etexilate with idarucizumab at the end of therapeutic time window

open access: diamondTurkish Journal of Emergency Medicine, 2020
Dabigatran is a direct oral anticoagulant that is widely used for stroke prevention in patients with atrial fibrillation. We report a case of an 80-year-old stroke patient on dabigatran for permanent atrial fibrillation, who presented with an initial ...
Gorana Vukorepa   +4 more
doaj   +3 more sources

The new way of Dabigatran reversal – Idarucizumab

open access: greenJournal of Education, Health and Sport, 2019
Since last few years a popularity of new oral anticoagulants significantly raised. There are following main direct oral anticoagulants (DOAC) used in therapy: Dabigatran, Rywaroxaban, Apixaban, Endoxaban.
Erwin Ciechański   +3 more
doaj   +4 more sources

Bleeding Risk of Anticoagulation Reversal Strategies Before Heart Transplantation: A Retrospective Comparative Cohort Study [PDF]

open access: yesJournal of Cardiovascular Development and Disease
Heart transplantation (HT) poses high bleeding risks, especially for patients on anticoagulation. This study evaluates the use of idarucizumab for dabigatran (DBG) reversal compared to vitamin K antagonist (VKA) strategies in HT. A retrospective analysis
Antonio Prieto-Romero   +10 more
doaj   +2 more sources

Cost-effectiveness of dabigatran for thromboembolic events prevention in atrial fibrillation patients in Chile [PDF]

open access: yesCost Effectiveness and Resource Allocation
Background Atrial fibrillation (AF) is the most common sustained arrhythmia in adults, associated with significant morbidity, mortality, and economic burden due to thromboembolic events.
Tomás Abbot   +5 more
doaj   +2 more sources

Idarucizumab for dabigatran reversal: A systematic review and meta-analysis of indications and outcomes

open access: hybridThrombosis Research, 2023
S F B van der Horst   +6 more
openalex   +2 more sources

Dabigatran accumulation in acute kidney injury: is more better than less to prevent bleeding? A case report [PDF]

open access: yesInternational Journal of Emergency Medicine
Dabigatran is an oral anticoagulant that is mainly renally excreted. Despite its efficacy in preventing thromboembolic events, concerns arise regarding bleeding complications in patients with acute kidney injury. Idarucizumab is its specific antidote and
Rafik Matbouli   +5 more
doaj   +2 more sources

Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution.

open access: goldPLoS ONE, 2019
BackgroundIdarucizumab is a humanized Fab fragment that specifically reverses dabigatran anticoagulation. In trauma, volume expanders are used for resuscitation to compensate for blood loss and hemorrhagic shock, but it is unknown whether volume ...
Oliver Grottke   +7 more
doaj   +3 more sources

Dabigatran-reversal failure using standard dose of idarucizumab: a systematic review and meta-analysis of cases [PDF]

open access: goldResearch and Practice in Thrombosis and Haemostasis, 2023
Sophie Melicine   +7 more
openalex   +2 more sources

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