Results 121 to 130 of about 137,716 (244)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, Volume 20, Issue 5, Page 1237-1252, May 2026.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Urodynamics assessment in patients with multiple sclerosis
BJUI Compass, Volume 7, Issue 5, May 2026.Abstract Objectives The aim of this study is to review initial urodynamics (UDS) findings in patients with multiple sclerosis (MS) related lower urinary tract symptoms, establish where UDS happen in treatment pathways and to evaluate the benefit of video over standard UDS.
Nicholas Faure Walker +19 more
wiley +1 more source
Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides
Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra +10 more
wiley +2 more sources
Cancer Medicine, Volume 15, Issue 5, May 2026.ABSTRACT Background To define the role of post‐mastectomy radiotherapy (PMRT) in triple‐negative breast cancer (TNBC), employing lymph node ratio (LNR, ratio of positive over excised lymph nodes) to offer personalized treatment strategies for this aggressively behaving cancer type. Methods The study included a total of 6474 women diagnosed with T1‐4 N1‐
Wei‐Hong Zheng +6 more
wiley +1 more source
MedComm, Volume 7, Issue 5, May 2026.Schematic diagram of mRNA‐lipid nanoparticles (mRNA‐LNP) and its functional mechanisms, applications, and challenges in cell engineering. This figure details the structural composition of mRNA‐LNPs and the delivery strategy, highlighting three core challenges.
Lina Li +9 more
wiley +1 more source
A preclinical setup for spatially fractionated radiation therapy with electrons
Medical Physics, Volume 53, Issue 5, May 2026.Abstract Background Spatially fractionated radiation therapy (SFRT) has therapeutic potential as a priming therapy which boosts tumor control. However, the optimal delivery and spatial fractionation parameters have not been deciphered and the mechanisms at play are not yet fully understood.
Edward R J F Taylor +5 more
wiley +1 more source
Small, Volume 22, Issue 26, 8 May 2026.This study presents an interpretable, lightweight hybrid deep learning model for real‐time analysis of breast cancer histopathology in IoMT‐enabled diagnostic systems. By integrating MobileNetV2 and EfficientNet‐B0 with a novel contextual recurrent attention module (CRAM), the framework achieves near‐perfect accuracy while providing transparent Grad ...
Roseline Oluwaseun Ogundokun +4 more
wiley +1 more source
GatorST: A Versatile Contrastive Meta‐Learning Framework for Spatial Transcriptomic Data Analysis
Small Methods, Volume 10, Issue 9, 8 May 2026.GatorST learns spatially informed embeddings for spatial transcriptomics by coupling two‐hop subgraph graph convolutions with cluster‐aware pseudo‐label supervision and episodic contrastive meta‐learning. The framework captures neighbor‐level topology and tissue‐wide expression semantics without heavy augmentations, delivering robust representations ...
Zhenhao Zhang +5 more
wiley +1 more source
Global Ecology and Biogeography, Volume 35, Issue 5, May 2026.ABSTRACT Aim To investigate the ecological and evolutionary mechanisms driving biodiversity in the Indo‐Malayan hotspots, with a particular focus on the roles of ancient hybridisation and historical climate in shaping species diversity. Location The Indo‐Malayan realm, particularly the Western Ghats‐Sri Lanka and Indo‐Burma biodiversity hotspots.
Marcos V. Dantas‐Queiroz +14 more
wiley +1 more source