Results 131 to 140 of about 1,848,862 (348)
A Heparin‐Functionalized Scaffold with HB‐EGF Immobilization for Tissue Engineering
Advanced Healthcare Materials, EarlyView.In this study, a heparin‐functionalized scaffold is designed for bio‐mimicking growth factors reservoir function of extracellular matrix. Due to the presence of heparin‐binding domain, heparin‐binding epidermal growth factor‐like growth factor (HB‐EGF) is effectively and spatially captured by heparin‐functionalized scaffold.Bowu Peng, Huajian Chen, Chengyu Lu, Tianjiao Zeng, Man Wang, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen +8 morewiley +1 more sourceInjectable Dual‐Crosslinked Poly(oligo(Ethylene Glycol) Methacrylate) Hydrogels Inspired by Mussel Adhesion for Cutaneous Wound Healing and Functional Tissue Regeneration
Advanced Healthcare Materials, EarlyView.Injectable POEGMA‐DA hydrogels, dual‐crosslinked via dopamine self‐polymerization and dynamic hydrazone bonds, provide a safer alternative to invasive wound closure methods and toxic bioadhesives. Mimicking skin‐like mechanics, they achieve effective tissue adhesion for acute dermal wounds, supporting improved healing outcomes, including reducing ...Gurpreet Kaur Randhawa, Meghan Kostashuk, Zhicheng Pan, Nils Nordstrom, Thomas Kalab, Erica Winterhelt, Todd Hoare +6 morewiley +1 more sourceThe IDEAL framework for surgical robotics: development, comparative evaluation and long-term monitoring
Nature MedicineHani J. Marcus, Pedro T Ramirez, D. Khan, H. Layard Horsfall, J. Hanrahan, Simon C. Williams, David J. Beard, Rani Bhat, Kenneth Catchpole, Andrew Cook, Katrina Hutchison, Janet Martin, Tom Melvin, Danail Stoyanov, M. Rovers, N. Raison, Prokar Dasgupta, David Noonan, D. Stocken, Georgia Sturt, A. Vanhoestenberghe, B. Vasey, P. McCulloch, Aswin Fanny Effy Christopher Marco Alan Karen Nigel Kath Chari Ficuciello Vayena Baber Zenati Kuntz Kerr Ho, Aswin Fanny Effy Christopher Marco Alan Karen Nigel Chari Ficuciello Vayena Baber Zenati Kuntz Kerr Ho, Aswin Chari, Fanny Ficuciello, E. Vayena, C. Baber, Marco A. Zenati, Alan Kuntz, Karen Kerr, N. Horwood, Katherine Ka-Wai Rich Bill Ferdinando Rodriquez Y. Pietro Ri Anderon Kwok Mahoney Peine Baena Valdastri Leparme, Katherine Anderon, Ka-Wai Kwok, Rich Mahoney, Bill Peine, Ferdinando Rodriquez Y. Baena, Pietro Valdastri, Richard Leparmentier, Len Evans, Rebecca Langley, Garnette Sanju Naeem Justin Mario M. James Alvin Bernard Sutherland Lama Soomro Collins Leitao Kinross Goh , Garnette R. Sutherland, Sanju Lama, Naeem Soomro, Justin Collins, Mario M. Leitao, James Kinross, Alvin Goh, Bernard Park, Matthias Rebecca Steven Duncan Laura Richard Jennifer Denny Weigl Randell Yule McPherson Pickup Skipworth Ange, Matthias Weigl, Rebecca Randell, Steven Yule, Duncan McPherson, L. Pickup, Richard J. E. Skipworth, Jennifer Anger, Denny Yu, Lora Cavuoto, Ann Bisantz, Tara Cohen, Mirre Guy Laura Alane Tammy J. Belen Cynthia Janneke Scholte Maddern Sampietro-Colom Clark Clifford Cor, Mirre Scholte, Guy Maddern, L. Sampietro-Colom, Alane Clark, Tammy J. Clifford, Belen Corbacho, Cynthia Iglesias, J. Grutters, Katrina Lesley Heather Len Sarah Alexander A. Rebecca Rob Hutchinson Booth Draper Evans Goering Kon Langley , Katrina Hutchinson, Lesley Booth, Heather Draper, Sarah Goering, Alexander A. Kon, Rob Sparrow, Kamran Deena Teodor Lars Ahmed Harji Grantcharov Konge, Kamran Ahmed, Deena Harji, T. Grantcharov, Lars Konge, Art Joel Arsenio Sedrakyan Horowitz Paez, A. Sedrakyan, Joel Horowitz, Arsenio Paez +88 moresemanticscholar +1 more sourceGrowth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds
Advanced Healthcare Materials, EarlyView.3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...Maria Pita‐Vilar, Diego Caicedo‐Valdés, Susana B. Bravo, Isabel Rodriguez‐Moldes, Salvador D. Aznar‐Cervantes, Angel Concheiro, Carmen Alvarez‐Lorenzo, Luis Diaz‐Gomez +7 morewiley +1 more sourceBiomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering
Advanced Healthcare Materials, EarlyView.This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...Sophia Lena Meermeyer, Arundhati Joshi, Constantin von Kaisenberg, Dorothea Brüggemann, Cornelia Lee‐Thedieck +4 morewiley +1 more sourceNew Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems
Advanced Healthcare Materials, EarlyView.This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao +10 morewiley +1 more sourcePlatelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification
Advanced Healthcare Materials, EarlyView.Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract
Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin +9 morewiley +1 more source