Results 101 to 110 of about 193,237 (301)

Pleasant ideals.

open access: yesNotre Dame Journal of Formal Logic, 1991
Let \(\kappa\) be a regular, uncountable cardinal and let \(I\) be an ideal on \(\kappa\) (all ideals considered contain all singletons and are \(
openaire   +4 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

It's in the Gene(alogy): Family, Storytelling, and Salvation

open access: yes, 2020
scholarly articleRabbi Dr. Stu Halpern's essay, "It's in the Gene(alogy): Family, Storytelling, and Salvation," was featured in the most recent edition of Conversations, published by the Institute for Jewish Ideas and ...
Halpern, Stuart
core  

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Egorov ideals [PDF]

open access: yes, 2023
We study Egorov ideals, that is ideals on $\omega$ for which the Egorov's theorem for ideal versions of pointwise and uniform convergences holds. We show that a non-pathological $\bf{\Sigma^0_2}$ ideal is Egorov if and only if it is countably generated ...
Kwela, Adam
core  

Discursive turns from 'Bildung' to managerialism

open access: yesEuropean Journal for Research on the Education and Learning of Adults, 2012
The article focuses on the struggles over ethos in academic adult education tradition that grows from the frameworks of student generations in Finnish adult education.
Karin Filander
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Results and Questions about Edge Ideals

open access: yes, 2017
In this talk we present some selected known results and new questions on edge ideals and their powers. We introduce and examine a new family of edge ideals associated to vertex-weighted oriented graphs that has been recently studied by E.
Villarreal, Rafael
core   +1 more source

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