Results 211 to 220 of about 1,900,562 (304)

Memoria Puerto de ideas 2024

Fundación Puerto de Ideas
core  

The effects of self-uncertainty on benevolent and malevolent creativity. [PDF]

BMC Psychol
Yuan H, Min H, Lu K, Xiang M, Hao N.
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Exposure to the ideas of others in idea generation.

Collaboration takes place everywhere in everyday life, and exposure to the ideas of others is a core process in collaboration. In this study, we investigated whether exposure to other people's ideas facilitates idea generation: 123 participants were asked to list as many ideas as possible to increase turnout in one of three conditions: constant ...
openaire   +1 more source

An AI system to help scientists write expert-level empirical software. [PDF]

Nature
Aygün E, Belyaeva A, Comanici G, Coram M, Cui H, Garrison J, Johnston R, Kast A, McLean CY, Norgaard P, Shamsi Z, Smalling D, Thompson J, Venugopalan S, Williams BP, He C, Martinson S, Plomecka M, Wei L, Zhou Y, Zhu QZ, Abraham M, Brand E, Bulanova A, Cardille JA, Co C, Ellsworth S, Joseph G, Kane M, Krueger R, Kartiwa J, Liebling D, Lueckmann JM, Raccuglia P, Wang XJ, Chou K, Manyika J, Matias Y, Platt JC, Dorfman L, Mourad S, Brenner MP.   +41 more
europepmc   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

The Role of Artificial Intelligence in Preservice Science Teachers' Analogical Reasoning: Evidence from Analogy Design. [PDF]

J Intell
Zorlu F.
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

The Marketplace of Ideas: Government Regulation Failures and Nonprofit Solutions

, 2007
Yi, Peter
core  

From means to meaningful: undertaking cluster analysis to develop health literacy profiles of people in Australian prisons. [PDF]

PLoS One
Gill SW, Cheng C, Bowman J, Shaw C, Osborne RH.   +4 more
europepmc   +1 more source