Results 91 to 100 of about 1,112,610 (386)

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Identical twins [PDF]

open access: yes, 1961
THE response to the Department\u27s appeal for identical twin calves has been gratifying, and so far this year five sets have been located and collected.
Department of Agriculture, Western Australia,
core   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Research with twins: The concept of emergenesis. [PDF]

open access: yes, 1982
Preliminaty findings from an on-going study of monozygotic twins reared apart (MZA) and data from a larger sample of twins reared together (MZT and DZT), indicate a surprisingly strong influence of genetic variation on aptitudes, psychophysiological ...
Lykken, David T.
core   +1 more source

The response to long-term overfeeding in identical twins.

open access: yesNew England Journal of Medicine, 1990
We undertook this study to determine whether there are differences in the responses of different persons to long-term overfeeding and to assess the possibility that genotypes are involved in such differences.
C. Bouchard   +9 more
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Does Learning to Read Improve Intelligence? A Longitudinal Multivariate Analysis in Identical Twins From Age 7 to 16

open access: yesChild Development, 2014
Evidence from twin studies points to substantial environmental influences on intelligence, but the specifics of this influence are unclear. This study examined one developmental process that potentially causes intelligence differences: learning to read ...
Stuart J. Ritchie   +2 more
semanticscholar   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Happiness: The Potential Power of Environment

open access: yesThe Baltic International Yearbook of Cognition, Logic and Communication, 2012
Many scientists have argued that they can determine to what extent human happiness levels are controlled by genes by comparing the average happiness levels of identical twins raised apart.
Clifford Sosis
doaj   +1 more source

Exploring pharmacodynamics of immunosuppresive agents in transplantation [PDF]

open access: yes, 2013
Supported by advancements in technology, surgical techniques and immunosuppressive drugs, solid organ transplantation has become the preferred solution to end stage organ failure.
Vafadari, R. (Ramin)
core   +1 more source

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