Results 91 to 100 of about 122,758 (325)
Marital Status and Unobserved Heterogeneity - Do twins suggest a genetic inheritance? [PDF]
The purpose of this study is to reveal the importance of unobserved heterogeneity on marital status. The results for monozygotic (identical) and dizygotic twins indicate an important genetic component in marital status.
Nilsson, William
core +1 more source
, 2004 Reg and Roger are twins, not identical, but two sides of the same ...
Connett, John E.
core +1 more source
Schizophrenia in identical twins
Indian Journal of Psychiatry, 2015 Byline: Choudhary. Narayan, Deep. Shikha, Shivendra. Shekhar Sir, Genetic factors are believed to play an important role in the causation of schizophrenia. While the lifetime risk in the general population is just below 1%, it is 6.5% infirst-degree relatives of patients [sup][1] and it rises to more than 40% in monozygotic twins of affected people ...
Narayan, Choudhary Laxmi +2 more
openaire +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Renal Urologic Anomalies Presenting In Adult Identical Twins
The Scientific World Journal, 2004 Two sets of identical adult twins recently presented to our hospital. In one case, the patients demonstrated (ipsilateral) renal agenesis. In the other, the patients presented approximately one year apart with symptomatic (ipsilateral) ureteropelvic ...
Robert A. Edelstein +2 more
doaj +1 more source
'Not-so-identical' twins with trisomy 21 and perimembranous ventricular septal defects
Türk Kardiyoloji Derneği Arşivi, 2016 Summary– While trisomy 21 is a common genetic disorder in singletons, the incidence among identical twins is very rare, occurring in approximately 1–2 per 1000 twin gestations. Trisomy 21 is associated with high incidence of congenital heart defects, and
Sarosh P Batlivala +3 more
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Identical twins with Blount's disease: 10-Year follow-up
Journal of Orthopaedic ReportsWe present the case of monozygous twin girls, aged 3 years and 2 months, each presenting with unilateral left sided Blount's disease. Despite shared genetics and similar initial presentations, one twin had early loss of fixation of her tibial osteotomy ...
Geoffrey T. Murphy +3 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source