Results 101 to 110 of about 1,112,610 (386)

Ageing And Cancer As Diseases Of Epigenesis [PDF]

open access: yes, 2009
Cancer and ageing are often said to be diseases of development. During the past fifty years, the genetic components of cancer and ageing have been intensely investigated since development, itself, was seen to be an epiphenomenon of the genome.
Gilbert, Scott F.
core   +2 more sources

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Sporadic case of incontinentia pigmenti in identical twins

open access: yesIndian Journal of Paediatric Dermatology, 2017
Incontinentia pigmenti (IP) is a rare genodermatoses with multisystem involvement. Monochorionic diamniotic twins are presented with characteristic skin manifestation and ocular and neurological involvement.
Shekhar Neema   +2 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Hereditary Resemblances of Lip Prints Among the Members of Biological Families

open access: yesJournal of Islamic International Medical College, 2022
Objective: To assess the resemblance of lip prints among the members of biological families, involving identical twins. Study Design: Descriptive study.
Aftab Alam Tanoli ,Ijaz Aziz , Khalil Ur Rehman , Nayella Nijat Bangesh , Qurrat Ul Ain , Farrukh Iqbal
doaj  

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Identical twins with Pierre Robin syndrome; unusual encounter

open access: yesElectronic Physician, 2017
New born babies could suffer from multiple craniofacial abnormalities, such as Pierre Robin syndrome, which consists of micrognathia and relative macroglossia with or without cleft palate. Although Pierre Robin syndrome is well described in literature,
Nabil Shdaifat   +4 more
doaj   +1 more source

Marital Status and Unobserved Heterogeneity - Do twins suggest a genetic inheritance? [PDF]

open access: yes
The purpose of this study is to reveal the importance of unobserved heterogeneity on marital status. The results for monozygotic (identical) and dizygotic twins indicate an important genetic component in marital status.
Nilsson, William
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Returns to Education: Evidence from UK Twins [PDF]

open access: yes
We use a new sample of UK female identical twins to estimate private economic returns to education. We report findings in three areas. First, we use identical twins, to control for family effects and genetic ability bias, and the education reported by ...
Denise Hawkes   +4 more
core  

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