Results 191 to 200 of about 122,758 (325)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Poorly differentiated thyroid carcinoma in identical twins: a report of two cases and review of the literature. [PDF]

Thyroid Res
El Masri A, El Moughrabi C, El Zouhbi A, Shebly A, Kassouf H, Natout M, Hazimeh Y, El Lakis M.   +7 more
europepmc   +1 more source

Identical twins with lumbosacral lipomyelomeningocele [PDF]

, 2014
Sara Hanaei, Farideh Nejat, Abolghasem Mortazavi, Zohreh Habibi, Arash Esmaeili, Mostafa El Khashab   +5 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Hypertrophic cardiomyopathy in identical twins: a case report with mismatch between genotype and phenotype. [PDF]

Eur Heart J Case Rep
Márquez-Murillo MF, Casillas-Muñoz JP, Sánchez-Contreras CA, Totomoch-Serra A, Mas-Bautista DA, Cano-Zarate R, Vázquez-Antona CA, Nava S.   +7 more
europepmc   +1 more source

Effect of natural killer cells on syngeneic bone marrow: in vitro and in vivo studies demonstrating graft failure due to NK cells in an identical twin treated by bone marrow transplantation [PDF]

, 1985
G. C. L. Goss, MA Wittwer, W.R. Bezwoda, Jean Herman, Alan S. Rabson, Lesley Seymour, Derman Dp, B. Mendelow   +7 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Kidney transplantation between identical twins with APOL1 homozygote risk alleles - a case report. [PDF]

Front Nephrol
Lei S, Shankar A, Sethi S, Lum EL.
europepmc   +1 more source

Osteosarcoma in One of Identical Twins: Three Cases Report and a Literature Review. [PDF]

Orthop Surg, 2021
Zhao J, Wang W, Liu Z, Li X, Cai Q, Yu X.   +5 more
europepmc   +1 more source

Implementation of Daugman’s Algorithm and Adaptive Noise Filtering Technique for Digital Recognition of Identical Twin using MATLAB

, 2018
Oleka Chioma Violet, Ugwu Chukwuka Kennedy   +1 more
openalex   +1 more source