Results 151 to 160 of about 24,451 (260)

Monitoring Parameter Identifiability With AUDI

, 1994
A simple, practical and unified method is presented for detecting the parameter identifiability problems due to non-persistent excitation, overparameterization and/or output feedback within the identified system. All the required information is generated
Steve Niu, Niu, Steve
core  

Towards precision EEG connectomics: Evaluating the benefits of dense sampling. [PDF]

Imaging Neurosci (Camb)
Graff K, Rai S, Yin S, Godfrey KJ, Merrikh D, Tansey R, Vanderwal T, Protzner AB, Bray S.   +8 more
europepmc   +1 more source

PhosSight: A Unified Deep Learning Framework Boosting and Accelerating Phosphoproteome Identification to Enable Biological Discoveries

Advanced Science, EarlyView.
PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang, Zhiyuan Cheng, Chengying She, Hongwei Zhao, Jiahui Zhang, Lin Lv, Zhihao Yan, Hongwen Zhu, Lizhuang Liu, Yan Fu, Xinpei Yi   +10 more
wiley   +1 more source

Identifiability Analysis Using Data Cloning

Lack of identifiability in statistical models may hinder unique inferential conclusions. Therefore, the search for parametric constraints that ensure identifiability is of utmost importance in statistics.
Márcia D’Elia Branco, José Augusto Sartori Junior   +1 more
core   +1 more source

Resolving parameter uncertainty in SIR models through population-level serological surveillance: A synthetic study. [PDF]

Infect Dis Model
Pant B, Levine ME, Nande A, Garcia RG, Dewey G, Link NB, Santillana M.   +6 more
europepmc   +1 more source

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

Advanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz, Saurabh Upadhyay, Renjie Zhu, Hongliang Duan, Moustafa T. Gabr   +4 more
wiley   +1 more source

Revisiting the General Identifiability Problem

We revisit the problem of general identifiability originally introduced in [Lee et al., 2019] for causal inference and note that it is necessary to add positivity assumption of observational distribution to the original definition of the problem. We show
Kivva, Yaroslav, Etesami, Jalal, Mokhtarian, Ehsan, Kiyavash, Negar   +3 more
core  

Automated Extraction of Multicomponent Alloy Data Using Large Language Models for Sustainable Design

Advanced Science, EarlyView.
A large language model (LLM) based pipeline is developed to automatically extract a comprehensive and accurate multicomponent alloy database from literature corpus. The extracted dataset is integrated with sustainability indicators to identify potential alloys that outperform existing industrial benchmark materials in terms of both performance and ...
Aravindan Kamatchi Sundaram, Mohit Chakraborty, Sai Mani Kumar Devathi, B. Pabitramohan Prusty, Rohit Batra   +4 more
wiley   +1 more source

A dependent and censored first hitting-time model with compound Poisson processes. [PDF]

Lifetime Data Anal
Escobar-Bach M, Popier A, Sahin M.
europepmc   +1 more source

Tumor‐Specific Delivery of CD28 siRNA via Lyso‐PC C‐16 Modified Lipid Nanoparticles Overcomes Anti‐PD‐1 Resistance by Remodeling Tumor Microenvironment

Advanced Science, EarlyView.
This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai, Keyu Wang, Jiali Fang, Shaorui Jia, Yansong Shi, Wanfeng Gao, Xinpeng Liu, Jiaqiang Li, Zenghui Cui, Yazhi Qian, Xiaosu Chen, Dan Ding, Xuetao Cao   +12 more
wiley   +1 more source