Results 151 to 160 of about 10,847,675 (330)
Ligand-Based Virtual Screening, Molecular Docking, Molecular Dynamics, and MM-PBSA Calculations towards the Identification of Potential Novel Ricin Inhibitors [PDF]
Fernanda D. Botelho +7 more
openalex +1 more source
Identification of patients with branch-duct intraductal papillary mucinous neoplasm and very low risk of cancer: multicentre study [PDF]
Domenico Tamburrino +18 more
openalex +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Modern threats of bioterrorism force the need to develop methods for rapid and accurate dentification of dangerous biological agents. Currently, there are many types of methods used in this field of studies that are based on immunological or genetic ...
Tomasz Mirski +7 more
doaj
Comprehensive characterizations of genetic diversity and demographic models of ethnolinguistically diverse Chinese populations are essential for elucidating their forensic characteristics and evolutionary past.
Chengliang Yang +10 more
doaj +1 more source
Identification and validation of aging-related genes in COPD based on bioinformatics analysis [PDF]
Shan Zhong +6 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Numerical Analysis and Experimental Verification of Damage Identification Metrics for Smart Beam with MFC Elements to Support Structural Health Monitoring [PDF]
Andrzej Koszewnik +2 more
openalex +1 more source

