Results 1 to 10 of about 927,518 (217)

Identification and biology of β‐secretase [PDF]

open access: bronzeJournal of Neurochemistry, 2011
J. Neurochem. (2012) 120 (Suppl. 1), 55–61.AbstractOur knowledge of the etiology of Alzheimer’s disease (AD) has advanced tremendously since the discovery of amyloid beta (Aβ) aggregation in diseased brains. Accumulating evidence suggests that Aβ plays a causative role in AD.
Patty C. Kandalepas, Robert Vassar
openalex   +4 more sources

Identification of Structural Domains Involved in Astrovirus Capsid Biology [PDF]

open access: greenViral Immunology, 2005
Coat proteins of non-enveloped, icosahedral viruses must perform a variety of functions during their life cycle such as assembly of the coat protein subunits into a closed shell, specific encapsidation of the viral nucleic acid, maturation of the capsid, interaction with host receptors, and disassembly to deliver the genetic information into the newly ...
Neel K. Krishna
openalex   +3 more sources

Identification of Key Proteins Involved in Axon Guidance Related Disorders: A Systems Biology Approach [PDF]

open access: greenarXiv, 2018
Axon guidance is a crucial process for growth of the central and peripheral nervous systems. In this study, 3 axon guidance related disorders, namely- Duane Retraction Syndrome (DRS) , Horizontal Gaze Palsy with Progressive Scoliosis (HGPPS) and Congenital fibrosis of the extraocular muscles type 3 (CFEOM3) were studied using various Systems Biology ...
Ishtiaque Ahammad
arxiv   +2 more sources

Target Identification Strategies in Plant Chemical Biology [PDF]

open access: yesFrontiers in Plant Science, 2014
The current needs to understand gene function in plant biology increasingly require more dynamic and conditional approaches opposed to classic genetic strategies.
Wim eDejonghe   +3 more
doaj   +5 more sources

Networks in Biology – From Identification, Analysis to Interpretation [PDF]

open access: hybrid, 2009
Over the last decade networks has become a unifying language in biology. Yet we are only in the beginning of understanding their significance for biology and their medical applications. I will talk about the diversity of biological networks composed either of genes, proteins, metabolites, or cells and the associated methods for finding these graphs in ...
Jesper Tegnér
openalex   +3 more sources

SYSTEM IDENTIFICATION CHALLENGES FROM SYSTEMS BIOLOGY

open access: bronzeIFAC Proceedings Volumes, 2006
Abstract Systems biology is the understanding through computational modelling of the function of biological systems. New high-throughput experimental technologies can measure simultaneously the levels of expression of thousands of genes. The challenge is to extract knowledge from these data sets in order to understand the regulatory machinery of the ...
Edmund J. Crampin
openalex   +3 more sources

Molecular Identification of Trypanosoma theileri and Biology of Trypanosomes

open access: bronzeWorld's Veterinary Journal, 2021
Trypanosoma theileri (T. theileri ) is a non-pathogenic, cosmopolitan, and commensal protozoa of cattle. The main objective of the current study was to investigate the biology and feasibility of T. theileri as a model candidate for the discovery of a novel drug. In the present study, the isolates of T.
Tewodros Fentahun, Jan Paeshuyse
openalex   +2 more sources

A Metatranscriptomics Survey of Microbial Diversity on Surfaces Post-Intervention of cleanSURFACES® Technology in an Intensive Care Unit

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Hospital-acquired infections (HAIs) pose a serious threat to patients, and hospitals spend billions of dollars each year to reduce and treat these infections.
Jeremy Chen See   +17 more
doaj   +1 more source

Anatomical Injection Guidelines for Glabellar Frown Lines Based on Ultrasonographic Evaluation

open access: yesToxins, 2021
When botulinum neurotoxin (BoNT) is injected to treat glabellar frown lines, the corrugator supercilia muscle (CSM) and procerus muscles are the main targets.
Soo-Bin Kim   +6 more
doaj   +1 more source

Analysis of facial ultrasonography images based on deep learning

open access: yesScientific Reports, 2022
Transfer learning using a pre-trained model with the ImageNet database is frequently used when obtaining large datasets in the medical imaging field is challenging.
Kang-Woo Lee   +3 more
doaj   +1 more source

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