Results 1 to 10 of about 5,558,576 (263)

Target Identification Strategies in Plant Chemical Biology [PDF]

open access: yesFrontiers in Plant Science, 2014
The current needs to understand gene function in plant biology increasingly require more dynamic and conditional approaches opposed to classic genetic strategies.
Wim eDejonghe   +3 more
doaj   +14 more sources

Identification and biology of β‐secretase [PDF]

open access: bronzeJournal of Neurochemistry, 2011
J. Neurochem. (2012) 120 (Suppl. 1), 55–61.AbstractOur knowledge of the etiology of Alzheimer’s disease (AD) has advanced tremendously since the discovery of amyloid beta (Aβ) aggregation in diseased brains. Accumulating evidence suggests that Aβ plays a causative role in AD.
Patty C. Kandalepas, Robert Vassar
openalex   +4 more sources

Mycosporine-Like Amino Acids (MAAs): Biology, Chemistry and Identification Features [PDF]

open access: goldPharmaceuticals, 2021
Mycosporines and mycosporine-like amino acids are ultra-violet-absorbing compounds produced by several organisms such as lichens, fungi, algae and cyanobacteria, especially upon exposure to solar ultraviolet radiation.
Vanessa Geraldes, Ernani Pinto
openalex   +2 more sources

Identification of Structural Domains Involved in Astrovirus Capsid Biology [PDF]

open access: greenViral Immunology, 2005
Coat proteins of non-enveloped, icosahedral viruses must perform a variety of functions during their life cycle such as assembly of the coat protein subunits into a closed shell, specific encapsidation of the viral nucleic acid, maturation of the capsid, interaction with host receptors, and disassembly to deliver the genetic information into the newly ...
Neel K. Krishna
openalex   +3 more sources

Identification and Characterisation of Technological Topics in the Field of Molecular Biology [PDF]

open access: yesScientometrics, 2008
This paper focuses on methodological approaches for characterising the specific topics within a technological field based on scientific literature data. We introduce a diachronic clustering analysis approach and some bibliometric indicators.
Besagni, Dominique   +4 more
core   +8 more sources

Networks in Biology – From Identification, Analysis to Interpretation [PDF]

open access: hybrid, 2009
Over the last decade networks has become a unifying language in biology. Yet we are only in the beginning of understanding their significance for biology and their medical applications. I will talk about the diversity of biological networks composed either of genes, proteins, metabolites, or cells and the associated methods for finding these graphs in ...
Jesper Tegnér
openalex   +3 more sources

Molecular Identification of Trypanosoma theileri and Biology of Trypanosomes

open access: bronzeWorld's Veterinary Journal, 2021
Trypanosoma theileri (T. theileri ) is a non-pathogenic, cosmopolitan, and commensal protozoa of cattle. The main objective of the current study was to investigate the biology and feasibility of T. theileri as a model candidate for the discovery of a novel drug. In the present study, the isolates of T.
Tewodros Fentahun, Jan Paeshuyse
openalex   +2 more sources

SYSTEM IDENTIFICATION CHALLENGES FROM SYSTEMS BIOLOGY

open access: bronzeIFAC Proceedings Volumes, 2006
Abstract Systems biology is the understanding through computational modelling of the function of biological systems. New high-throughput experimental technologies can measure simultaneously the levels of expression of thousands of genes. The challenge is to extract knowledge from these data sets in order to understand the regulatory machinery of the ...
Edmund J. Crampin
openalex   +3 more sources

Target identification and mechanism of action in chemical biology and drug discovery [PDF]

open access: greenNature Chemical Biology, 2013
Monica Schenone   +3 more
openalex   +2 more sources

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