Results 81 to 90 of about 4,294,478 (314)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Controlling platinum, ruthenium, and osmium reactivity for anticancer drug design [PDF]
, 2009 The main task of the medicinal chemist is to design molecules that interact specifically with derailed or degenerating processes in a diseased organism, translating the available knowledge of pathobiochemical and physiological data into chemically ...
Bruijnincx, Pieter C. A., Sadler, P. J.
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
International Journal of Development Education and Global Learning, 2013 We examine the influence of factual and perceived world knowledge on global citizenship identification. Perceived world knowledge directly predicted global citizenship identification, while factual world knowledge did not (Study 1).
doaj +2 more sources
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Does Identification with the Firm and Profession Mitigate Outcome Effect on Auditors’ Decisions?
Audit Financiar, 2020 The paper examines whether auditors’ identification with the organization or with the profession will influence the use of outcome knowledge when reviewing audits.
doaj +1 more source
Identification of climate policy knowledge needs: a stakeholders consultation approach [PDF]
International Journal of Climate Change Strategies and Management, 2018 Purpose - The purpose of this paper is to identify knowledge gaps on insinuations of possible directions of European Union (EU) and international climate policies.
Charikleia Karakosta +2 more
doaj +1 more source
Knowledge Based Identification of Non-Linear Systems
IFAC-PapersOnLine, 2018 Abstract In order to model uncertainty involved into a real-world process, a general approach combining both analytical and expert knowledge-based techniques to identify a multi-input multi-output non-linear system model is proposed. The approach leads to using a new type of stochastic dependence of random processes, involving corresponding expert ...
openaire +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Statement of the Problem of Recognition of the Users in E-learning Systems
Безопасность информационных технологий, 2013 The aim of this paper is to research the characteristics of the recognition of the users in E-learning systems and to explain the use of the combined method on basis of the known means of identification and authentication.
Victor Sergeevich Gorbatov +2 more
doaj