Results 231 to 240 of about 1,167,811 (290)

Recommendations for HLA Genotyping Data Standards and Clinical Laboratory Staffing Considerations. [PDF]

HLA
Spierings E, Brown NK, Latham K, Robinson J, Melchers M, Askar M, Morris GP, Weimer E, Maiers M, Madbouly A.   +9 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Longitudinal mental health data collected via the Corona Health smartphone app during COVID-19. [PDF]

Sci Data
Winter M, Vogel C, Schobel J, Schlüter M, Baumeister H, Terhorst Y, Schlee W, Langguth B, Heuschmann P, Cohrdes C, Pryss R.   +10 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Zamtocabtagene autoleucel: dual CD20-CD19 targeting for NHL. [PDF]

Blood Adv
Srinagesh HK, Muffly LS.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Childhood Cancer Data Initiative Participant Index: Mapping Pediatric Cancer Data to Facilitate Cross-Study Integrated Analysis. [PDF]

JCO Clin Cancer Inform
Jagu S, Guidry Auvil JM, Cunningham MD, Jimenez RF, Ferguson ML, Smith MA, Hawkins DS, Alonzo TA, Beeles T, Widemann BC, Kibbe WA, Reaman GH.   +11 more
europepmc   +1 more source

One-Legged Stand Test: Synchronized Motion Capture, Force Plate, and Radar Dataset for Fall-Risk. [PDF]

Sci Data
Copeland D, Zhang X, Linton E, Mori B, Lugaro H, Anthony BW.   +5 more
europepmc   +1 more source

Muscle Proteomic Dataset of A Threatened Indian walking catfish, Clarias magur (Hamilton 1822) Exposed to Thermal Stress. [PDF]

Sci Data
Singh PJ, Batta A, Srivastava SK.
europepmc   +1 more source