Results 141 to 150 of about 256,860 (287)

Validating claims-based algorithms for a systemic lupus erythematosus diagnosis in Medicare data for informed use of the Lupus Index: a tool for geospatial research

open access: yesLupus Science and Medicine
Objective This study aimed to validate claims-based algorithms for identifying SLE and lupus nephritis (LN) in Medicare data, enhancing the use of the Lupus Index for geospatial research on SLE prevalence and outcomes.Methods We retrospectively evaluated
Jim C Oates   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Selected Aspects of the Unfair Struggle for Job Positions

open access: yesActa Academiae Beregsasiensis. Economics
The topic of unfair competition for job positions is a significant yet underexplored issue within the domains of managerial and business ethics. This study aims to shed light on this problem by examining three core themes related to unethical struggles ...
Мarian Аmbrozy, Zuzana Kuběnová
doaj   +1 more source

Graphs admitting (1, ≤ 2)-identifying codes [PDF]

open access: yes
Master of ScienceDepartment of MathematicsSarah ReznikoffA (1, ≤ 2)-identifying code is a subset of the vertex set C of a graph such that each pair of vertices intersects C in a distinct way.
Lang, Julie
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Vertex Identifying Codes for Fault Isolation in Communication Networks [PDF]

open access: yes, 2008
Rapid advances in semiconductor technology have made possible the design of systems with a large number of components. It is difficult to build such systems without defects. Thus fault diagnosis, testing and tolerance have become issues of great interest
Min Xu   +3 more
core  

International classification of disease, tenth revision (ICD-10) codes for identifying study population. [PDF]

open access: yes
International classification of disease, tenth revision (ICD-10) codes for identifying study population.
Yvonne Roca (14539364)   +5 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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