Results 161 to 170 of about 6,561,712 (300)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Identities in movement: thinking the national culture by means of the cinema
A questão da formação das identidades é muito relevante para os chamados estudos culturais em nossos dias. Em especial as identidades nacionais, vinculadas automaticamente às diversas manifestações da cultura popular e midiática, têm ganhado cada vez mais espaço em diversos campos de pesquisa.
openaire +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
How do cultural repertoires shape sustainable teacher identity? Confucian striving and Daoist release among Chinese pre-service teachers. [PDF]
Lin X, Tan Q, Xiong B.
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Identity Theory and College Hookup Culture
Hooking up can carry a vast array of definitions, embody a multitude of implications, and is still somehow an almost unavoidable part of college life. The present study applies identity theory to the relatively new culture of sex and dating at college ...
Hayes, Whitney Ann
core
When school engagement rhymes with roots breach. Adolescents and school avoidance in transcultural situations. [PDF]
Rizzi AT, Moro MR, Radjack R.
europepmc +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Psychosocial Pathways Linking Patriarchal Family Culture to Mental Health Among Transgender and Nonbinary Adults. [PDF]
Starowicz A, Wnuk A, Oleksy T, Gambin M.
europepmc +1 more source

